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Accrued Expenses and Other Current Liabilities (Detail) (USD $)
In Thousands, unless otherwise specified
Dec. 31, 2013
Dec. 31, 2012
Accrued Expenses and Other Current Liabilities [Line Items]    
Salary and related expenses $ 12,193 $ 10,074
Research and clinical trial costs 1,311 5,995
Accrued interest 2,082 4,533
Construction in progress 342 3,878
Other 5,706 1,297
Accrued expenses and other current liabilities $ 21,634 $ 25,777