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Fair Value of Financial Instruments - Additional Information (Detail) (USD $)
 0 Months Ended 12 Months Ended 12 Months Ended 0 Months Ended 12 Months Ended 0 Months Ended 12 Months Ended
Dec. 20, 2012
Oct. 18, 2012
Dec. 31, 2011
Dec. 31, 2010
Dec. 31, 2013
Derivative
Dec. 31, 2012
Dec. 31, 2013
Senior convertible notes due December 15, 2013
Dec. 31, 2013
Senior convertible notes due August 15 2015
Dec. 31, 2013
Deerfield
Jul. 01, 2013
Income Approach Valuation Technique
Milestone Rights Liability
Dec. 31, 2013
Income Approach Valuation Technique
Milestone Rights Liability
Jul. 01, 2013
Income Approach Valuation Technique
Commitment Asset
Jul. 01, 2013
Income Approach Valuation Technique
Scenario, Forecast
Milestone Rights Liability
Dec. 31, 2011
Foreign Exchange Contract
Dec. 31, 2010
Foreign Exchange Contract
Dec. 31, 2013
Major Transaction Put Option
Dec. 31, 2013
Conversion option feature
Dec. 31, 2013
Acceleration upon a Legal Judgment Against the Company in Excess of $100,000
Dec. 31, 2013
Money market funds
Dec. 31, 2012
Money market funds
Fair Value of Financial Instruments [Line Items]                                        
Cash equivalents         $ 70,800,000 $ 61,800,000                         $ 67,700,000 $ 60,800,000
Senior convertible notes, balance outstanding         98,439,000 212,026,000 0                          
Long-term historical volatility rate               65.00%                        
Market discount rate 1.50% 2.30%               12.40% 12.70% 12.00% 17.50%              
Number of embedded derivatives contained in facility financing obligation         4                              
Facility arrangement amount to be paid in excess of legal judgment                 100,000                      
Estimated fair value of the embedded derivative , cumulative probability percentage                               0.80% 0.00% 0.10%    
Foreign exchange hedging contracts notional amount                           0 25,500,000          
Unrealized loss on foreign exchange hedging       200,000                                
Gain on foreign exchange hedging contract     $ 1,300,000 $ (1,600,000)