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Fair Value of Financial Instruments - Additional Information (Detail) (USD $)	3 Months Ended						0 Months Ended				3 Months Ended
	Mar. 31, 2014	Mar. 31, 2013	Dec. 31, 2013	Dec. 31, 2012	Jul. 01, 2013 Senior convertible notes due December 31, 2019	Feb. 28, 2014 Senior convertible notes due December 31, 2019 Fair Value, Inputs, Level 3	Jul. 01, 2013 Senior convertible notes due December 31, 2019 Fair Value, Inputs, Level 3 Income Approach Valuation Technique	Jul. 01, 2013 Senior convertible notes due December 31, 2019 Fair Value, Inputs, Level 3 Income Approach Valuation Technique Tranche One	Mar. 31, 2014 Senior convertible notes due August 15, 2015	Aug. 18, 2010 Senior convertible notes due August 15, 2015	Mar. 31, 2014 Commitment Asset Fair Value, Inputs, Level 3 Income Approach Valuation Technique	Mar. 31, 2014 Milestone Rights Liability Fair Value, Inputs, Level 3 Income Approach Valuation Technique
Fair Value of Financial Instruments [Line Items]
Cash equivalents	$ 35,759,000	$ 28,005,000	$ 70,790,000	$ 61,840,000
Cash equivalents, money market funds	34,900,000		67,700,000
Senior notes, effective interest rate									5.75%	5.75%
Market discount rate							12.70%	12.50%			12.00%	17.50%
Additional commitment asset					2,900,000	2,900,000
Percentage of market yield						11.90%
Transfers of assets between fair value measurement	0	0
Transfers of liabilities between fair value measurement	$ 0	$ 0

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Commitment Assets, Market Yields

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Loan Commitment Asset Fair Value

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Amount of currency on hand as well as demand deposits with banks or financial institutions. Includes other kinds of accounts that have the general characteristics of demand deposits. Also includes short-term, highly liquid investments that are both readily convertible to known amounts of cash and so near their maturity that they present insignificant risk of changes in value because of changes in interest rates. Excludes cash and cash equivalents within disposal group and discontinued operation.

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Reference 1: http://www.xbrl.org/2003/role/presentationRef

-Publisher FASB

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-Name Accounting Standards Codification

-Glossary Cash Equivalents

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Contractual interest rate for funds borrowed, under the debt agreement.

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Interest rate used to find the present value of an amount to be paid or received in the future as an input to measure fair value. For example, but not limited to, weighted average cost of capital (WACC), cost of capital, cost of equity and cost of debt.

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Amount of transfer of financial instrument classified as an asset into (out of) level 3 of the fair value hierarchy.

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Amount of transfers of financial instrument classified as a liability into (out of) level 3 of the fair value hierarchy.

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Investment in short-term money-market instruments (such as commercial paper, banker's acceptances, repurchase agreements, government securities, certificates of deposit, and so forth) which are highly liquid (that is, readily convertible to known amounts of cash) and so near their maturity that they present an insignificant risk of changes in value because of changes in interest rates. Generally, only investments with original maturities of three months or less qualify as cash equivalents by definition. Original maturity means an original maturity to the entity holding the investment. For example, both a three-month US Treasury bill and a three-year Treasury note purchased three months from maturity qualify as cash equivalents. However, a Treasury note purchased three-years ago does not become a cash equivalent when its remaining maturity is three months.

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