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Condensed Consolidated Statements of Cash Flows (USD $) In Thousands, unless otherwise specified | 6 Months Ended | 280 Months Ended
--- | --- | ---
Jun. 30, 2014 | Jun. 30, 2013 | Jun. 30, 2014
CASH FLOWS FROM OPERATING ACTIVITIES: |  |  |
Net loss | $ (125,422) | $ (87,089) | $ (2,421,824)
Adjustments to reconcile net loss to net cash used in operating activities: |  |  |
Depreciation and accretion | 12,614 | 6,668 | 153,448
Stock-based compensation expense | 51,583 | 15,362 | 234,687
Stock expense for shares issued pursuant to research agreement |  |  | 3,018
(Gain) loss on sale, abandonment/disposal or impairment of property and equipment |  | 686 | 25,070
Accrued interest on investments, net of amortization of discounts |  |  | (191)
In-process research and development |  |  | 19,726
Goodwill impairment |  |  | 151,428
Loss on available-for-sale securities |  |  | 990
Write-off of derivative liability | (363) |  | (363)
Litigation settlement in stock |  |  | 6,494
Fair value of forward purchase contract |  |  | 1,237
Other, net |  | (2) | 1,101
Changes in assets and liabilities: |  |  |
State research and development credit exchange receivable | (165) | (157) | (462)
Prepaid expenses and other current assets | 1,789 | 1,337 | (1,746)
Other assets | (131) |  | (361)
Accounts payable | 1,567 | (974) | 4,914
Accrued expenses and other current liabilities | (3,315) | 2,398 | 35,409
Other liabilities | 1,435 |  | 2,024
Net cash used in operating activities | (60,408) | (61,771) | (1,785,401)
CASH FLOWS FROM INVESTING ACTIVITIES: |  |  |
Purchase of marketable securities |  |  | (796,779)
Sales and maturities of marketable securities |  |  | 796,393
Purchase of property and equipment | (9,667) | (1,591) | (345,400)
Proceeds from sale of property and equipment |  |  | 454
Net cash used in investing activities | (9,667) | (1,591) | (345,332)
CASH FLOWS FROM FINANCING ACTIVITIES: |  |  |
Issuance of common stock and warrants, net of issuance costs | 20,622 | 30,499 | 1,564,946
Collection of Series C convertible preferred stock subscriptions receivable |  |  | 50,000
Issuance of Series B convertible preferred stock for cash |  |  | 15,000
Cash received for common stock to be issued |  |  | 3,900
Repurchase of common stock |  |  | (1,028)
Put shares sold to majority stockholder |  |  | 623
Borrowings under lines of credit |  |  | 4,220
Payment of 2013 notes |  |  | (115,000)
Proceeds from notes receivables |  |  | 1,742
Proceeds from issuance of facility financing obligation & milestone rights |  |  | 119,500
Proceeds from issuance of Tranche B of the facility financing obligation | 20,000 |  | 20,000
Facility financing obligation & milestone rights issuance costs |  |  | (598)
Borrowings on notes payable to principal stockholder |  |  | 387,750
Principal payments on notes payable to principal stockholder |  |  | (70,000)
Borrowings on notes payable |  |  | 3,460
Principal payments on notes payable |  |  | (1,667)
Proceeds from senior convertible notes |  |  | 207,050
Payment of employment taxes related to vested restricted stock units | (123) | (448) | (17,951)
Net cash provided by financing activities | 40,499 | 30,051 | 2,171,947
NET INCREASE (DECREASE) IN CASH AND CASH EQUIVALENTS | (29,576) | (33,311) | 41,214
CASH AND CASH EQUIVALENTS, BEGINNING OF PERIOD | 70,790 | 61,840 |
CASH AND CASH EQUIVALENTS, END OF PERIOD | 41,214 | 28,529 | 41,214
SUPPLEMENTAL CASH FLOWS DISCLOSURES: |  |  |
Cash paid for income taxes |  |  | 26
Interest paid in cash, net of amounts capitalized | 5,296 | 5,006 | 77,900
Accretion on redeemable convertible preferred stock |  |  | (952)
Issuance of common stock upon conversion of notes payable |  |  | 3,331
Increase in additional paid-in capital resulting from merger |  |  | 171,154
Issuance of common stock for notes receivable |  |  | 2,758
Issuance of common stock pursuant to conversion of facility financing obligation | 93,500 |  | 100,000
Issuance of put option by stockholder |  |  | (2,949)
Put option redemption by stockholder |  |  | 1,921
Issuance of Series C convertible preferred stock subscriptions |  |  | 50,000
Issuance of Series A redeemable convertible preferred stock |  |  | 4,296
Conversion of Series A redeemable convertible preferred stock |  |  | (5,248)
Non-cash construction in progress and property and equipment | 2,965 | 4,605 | 2,965
Capitalization of interest on note payable to principal stockholder |  |  | 22,105
Reduction of principal on note payable to principal stockholder upon issuance of common stock and exercise of warrants |  |  | 290,334
Forward purchase contract contribution to APIC |  |  | 29,317
Reclassification of forward purchase contract to APIC |  |  | 28,080
Reclassification of share-based awards to liability | (19,926) |  | (19,926)
Tranche B Commitment Asset | $ 1,753 |  | $ 1,753

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