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Common and Preferred Stock - Additional Information (Detail) (USD $) | 9 Months Ended | 283 Months Ended |  |  |  |  | 9 Months Ended | 12 Months Ended |  | 0 Months Ended |
--- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | ---
Sep. 30, 2014 | Sep. 30, 2014 | Dec. 31, 2013 | Sep. 30, 2014 Senior convertible notes due August 15, 2015 | Dec. 31, 2013 Senior convertible notes due August 15, 2015 | Aug. 18, 2010 Senior convertible notes due August 15, 2015 | Sep. 30, 2014 Deerfield Senior convertible notes due December 31, 2019 | Dec. 31, 2013 Deerfield Senior convertible notes due December 31, 2019 | Feb. 28, 2014 Deerfield Senior convertible notes due December 31, 2019 | Jul. 01, 2013 Deerfield Senior convertible notes due December 31, 2019 Notes Issued in Four Equal Tranches Tranche | Jul. 01, 2013 Deerfield Senior convertible notes due December 31, 2019 Notes Issued in Four Equal Tranches
Class of Stock [Line Items] |  |  |  |  |  |  |  |  |  |  |
Common stock, shares authorized | 550,000,000 | 550,000,000 | 550,000,000 |  |  |  |  |  |  |  |
Common stock, par value | $ 0.01 | $ 0.01 | $ 0.01 |  |  |  |  |  |  |  |
Undesignated preferred stock, shares authorized | 10,000,000 | 10,000,000 |  |  |  |  |  |  |  |  |
Undesignated preferred stock, par value | $ 0.01 | $ 0.01 | $ 0.01 |  |  |  |  |  |  |  |
Common stock, shares issued | 405,469,034 | 405,469,034 | 369,391,972 |  |  |  |  |  |  |  |
Common stock, shares outstanding | 405,469,034 | 405,469,034 | 369,391,972 |  |  |  |  |  |  |  |
Common stock loaned under share lending agreement, shares | 9,000,000 | 9,000,000 | 9,000,000 |  |  |  |  |  |  |  |
Undesignated preferred stock, shares outstanding | 0 | 0 | 0 |  |  |  |  |  |  |  |
Principal amount |  |  |  | $ 100,000,000 | $ 100,000,000 | $ 100,000,000 |  |  |  |  | $ 160,000,000
Nominal lending fee | $ 0.01 |  |  |  |  |  |  |  |  |  |
Maximum sales amount under the agreement |  |  |  |  |  |  |  |  |  |  | 160,000,000
Number of equal tranches |  |  |  |  |  |  |  |  |  | 4 |
Debt facility periodic principal amount |  |  |  |  |  |  |  |  |  |  | 40,000,000
Aggregate principal amount of convertible notes |  |  |  |  |  |  | 0 |  | 60,000,000 |  |
Common shares issuable upon conversion |  |  |  |  |  |  | 18,616,304 |  | 12,000,000 |  |
Conversion price of shares |  |  |  |  |  | $ 6.80 |  |  | $ 5.00 |  |
Amount of common shares issued upon conversion | 93,500,000 | 100,000,000 |  |  |  |  | 100,000,000 |  |  |  |
Loss on debt conversion |  |  |  |  |  |  | $ 6,400,000 | $ 600,000 |  |  |

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