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Common and Preferred Stock - Additional Information (Detail) (USD $)
 9 Months Ended 283 Months Ended 9 Months Ended 12 Months Ended 0 Months Ended
Sep. 30, 2014
Sep. 30, 2014
Dec. 31, 2013
Sep. 30, 2014
Senior convertible notes due August 15, 2015
Dec. 31, 2013
Senior convertible notes due August 15, 2015
Aug. 18, 2010
Senior convertible notes due August 15, 2015
Sep. 30, 2014
Deerfield
Senior convertible notes due December 31, 2019
Dec. 31, 2013
Deerfield
Senior convertible notes due December 31, 2019
Feb. 28, 2014
Deerfield
Senior convertible notes due December 31, 2019
Jul. 01, 2013
Deerfield
Senior convertible notes due December 31, 2019
Notes Issued in Four Equal Tranches
Tranche
Jul. 01, 2013
Deerfield
Senior convertible notes due December 31, 2019
Notes Issued in Four Equal Tranches
Class of Stock [Line Items]                      
Common stock, shares authorized 550,000,000 550,000,000 550,000,000                
Common stock, par value $ 0.01 $ 0.01 $ 0.01                
Undesignated preferred stock, shares authorized 10,000,000 10,000,000                  
Undesignated preferred stock, par value $ 0.01 $ 0.01 $ 0.01                
Common stock, shares issued 405,469,034 405,469,034 369,391,972                
Common stock, shares outstanding 405,469,034 405,469,034 369,391,972                
Common stock loaned under share lending agreement, shares 9,000,000 9,000,000 9,000,000                
Undesignated preferred stock, shares outstanding 0 0 0                
Principal amount       $ 100,000,000 $ 100,000,000 $ 100,000,000         $ 160,000,000
Nominal lending fee $ 0.01                    
Maximum sales amount under the agreement                     160,000,000
Number of equal tranches                   4  
Debt facility periodic principal amount                     40,000,000
Aggregate principal amount of convertible notes             0   60,000,000    
Common shares issuable upon conversion             18,616,304   12,000,000    
Conversion price of shares           $ 6.80     $ 5.00    
Amount of common shares issued upon conversion 93,500,000 100,000,000         100,000,000        
Loss on debt conversion             $ 6,400,000 $ 600,000