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Facility Agreement - Additional Information (Detail) (USD $)
9 Months Ended 283 Months Ended 9 Months Ended 0 Months Ended 0 Months Ended 9 Months Ended
Sep. 30, 2014
Sep. 30, 2014
Dec. 31, 2013
Sep. 30, 2014
Tranche B notes
Jul. 01, 2013
Senior convertible notes due December 31, 2019
Sep. 30, 2014
Senior convertible notes due December 31, 2019
Tranche B notes
Maximum
Jul. 01, 2013
Deerfield
Milestone Rights Liability
Maximum
Sep. 30, 2014
Deerfield
Senior convertible notes due December 31, 2019
Feb. 28, 2014
Deerfield
Senior convertible notes due December 31, 2019
Sep. 30, 2014
Deerfield
Senior convertible notes due December 31, 2019
Maximum
Facility Agreement
Jul. 01, 2013
Deerfield
Senior convertible notes due December 31, 2019
Notes Issued in Four Equal Tranches
Tranche
Sep. 30, 2014
Deerfield
Senior convertible notes due December 31, 2019
Notes Issued in Four Equal Tranches
Jul. 01, 2013
Deerfield
Senior convertible notes due December 31, 2019
Notes Issued in Four Equal Tranches
Sep. 30, 2014
Deerfield
Senior convertible notes due December 31, 2019
Fourth tranche
Feb. 28, 2014
Deerfield
Senior convertible notes due December 31, 2019
Tranche B notes
Sep. 23, 2014
Deerfield
Senior convertible notes due December 31, 2019
Tranche B notes
Jul. 18, 2014
Deerfield
Senior convertible notes due December 31, 2019
Tranche B notes
May 06, 2014
Deerfield
Senior convertible notes due December 31, 2019
Tranche B notes
Feb. 28, 2014
Deerfield
Senior convertible notes due December 31, 2019
Tranche B notes
Mar. 31, 2014
Deerfield
Senior convertible notes due December 31, 2019
Tranche Three
Apr. 30, 2014
Deerfield
Senior convertible notes due December 31, 2019
Tranche One
Mar. 31, 2014
Deerfield
Senior convertible notes due December 31, 2019
Tranche One
Sep. 30, 2014
Deerfield
Senior convertible notes due December 31, 2019
Milestone Rights Liability
Jul. 01, 2013
Deerfield
Senior convertible notes due December 31, 2019
Milestone Rights Liability
Sep. 30, 2014
Deerfield
Senior convertible notes due December 31, 2019
Tranche One and Tranche Three
Debt Instrument [Line Items]                                                  
Debt facility principal amount                         $ 160,000,000           $ 90,000,000            
Number of equal tranches                     4                            
Debt facility periodic principal amount                         40,000,000                        
Senior notes, effective interest rate                         9.75%     8.75%     9.75%           11.63%
Principal amount of notes purchased                       160,000,000   160,000,000     40,000,000 20,000,000              
Repayment as a percentage of original principal amount                                     25.00%            
Debt instrument maturity date                             Dec. 31, 2019                    
Maximum secured loan facility                         160,000,000     175,000,000                  
Aggregate principal amount of convertible notes               0 60,000,000                     40,000,000 7,500,000 12,500,000      
Common shares issuable upon conversion               18,616,304 12,000,000                                
Maximum available amount of credit facility under covenant restrictions                   25,000,000                              
Contingent liability for milestone payments             90,000,000                               1,900,000    
Short term liability     102,300,000                                       9,200,000 3,200,000  
Long term liability 72,625,000 72,625,000                                         8,900,000 13,100,000  
Required payment pursuant to the terms of the Milestone Agreement                                             5,000,000    
Commitment asset at fair value       2,921,000 2,900,000 70,000,000           0           1,800,000              
Amount of common shares issued upon conversion $ 93,500,000 $ 100,000,000           $ 100,000,000