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Fair Value of Financial Instruments - Additional Information (Detail) (USD $)	9 Months Ended							0 Months Ended							9 Months Ended		9 Months Ended
	Sep. 30, 2014	Sep. 30, 2013	Dec. 31, 2013	Dec. 31, 2012	Sep. 30, 2014 Tranche B notes	Jul. 01, 2013 Senior convertible notes due December 31, 2019	Feb. 28, 2014 Senior convertible notes due December 31, 2019 Fair Value, Inputs, Level 3 Tranche B notes	Dec. 31, 2013 Senior convertible notes due December 31, 2019 Fair Value, Inputs, Level 3 Income Approach Valuation Technique	Sep. 30, 2014 Senior convertible notes due December 31, 2019 Fair Value, Inputs, Level 3 Income Approach Valuation Technique Tranche B notes	Jul. 01, 2013 Senior convertible notes due December 31, 2019 Fair Value, Inputs, Level 3 Income Approach Valuation Technique Tranche B notes	Sep. 30, 2014 Senior convertible notes due December 31, 2019 Fair Value, Inputs, Level 3 Income Approach Valuation Technique Tranche One and Tranche Four Notes	Jul. 18, 2014 Deerfield Senior convertible notes due December 31, 2019 Tranche B notes	May 06, 2014 Deerfield Senior convertible notes due December 31, 2019 Tranche B notes	Sep. 30, 2014 Deerfield Senior convertible notes due December 31, 2019 Notes Issued in Four Equal Tranches	Sep. 30, 2014 Commitment Asset Fair Value, Inputs, Level 3 Income Approach Valuation Technique	Sep. 30, 2014 Milestone Rights Liability Fair Value, Inputs, Level 3	Sep. 30, 2014 Milestone Rights Liability Fair Value, Inputs, Level 3 Income Approach Valuation Technique
Fair Value of Financial Instruments [Line Items]
Cash equivalents	$ 172,465,000	$ 93,803,000	$ 70,790,000	$ 61,840,000
Cash equivalents, money market funds	169,700,000		67,700,000
Company's longer-term historical volatility rate	85.00%
Market discount rate								12.70%	11.90%	11.90%	12.40%				12.00%		17.50%
Fair value of Milestone Rights																23,100,000
Principal amount of notes purchased												40,000,000	20,000,000	160,000,000
Additional commitment asset					2,921,000	2,900,000	2,900,000						1,800,000	0
Percentage of market yield							11.90%
Commitment asset, debt discount													1,200,000
Transfers of assets between fair value measurement	0	0
Transfers of liabilities between fair value measurement	$ 0	$ 0

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Loan Commitment Asset Fair Value

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Amount of currency on hand as well as demand deposits with banks or financial institutions. Includes other kinds of accounts that have the general characteristics of demand deposits. Also includes short-term, highly liquid investments that are both readily convertible to known amounts of cash and so near their maturity that they present insignificant risk of changes in value because of changes in interest rates. Excludes cash and cash equivalents within disposal group and discontinued operation.

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Face (par) amount of the original debt instrument that was repurchased.

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The amount of debt discount that was originally recognized at the issuance of the instrument that has yet to be amortized.

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Measure of dispersion, in percentage terms (for instance, the standard deviation or variance), for a given stock price.

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Interest rate used to find the present value of an amount to be paid or received in the future as an input to measure fair value. For example, but not limited to, weighted average cost of capital (WACC), cost of capital, cost of equity and cost of debt.

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Amount of transfer of financial instrument classified as an asset into (out of) level 3 of the fair value hierarchy.

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Fair value of financial and nonfinancial obligations.

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Investment in short-term money-market instruments (such as commercial paper, banker's acceptances, repurchase agreements, government securities, certificates of deposit, and so forth) which are highly liquid (that is, readily convertible to known amounts of cash) and so near their maturity that they present an insignificant risk of changes in value because of changes in interest rates. Generally, only investments with original maturities of three months or less qualify as cash equivalents by definition. Original maturity means an original maturity to the entity holding the investment. For example, both a three-month US Treasury bill and a three-year Treasury note purchased three months from maturity qualify as cash equivalents. However, a Treasury note purchased three-years ago does not become a cash equivalent when its remaining maturity is three months.

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