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Collaborative Arrangement - Additional Information (Detail) (License and Collaboration Agreement with Sanofi, USD $)
0 Months Ended 3 Months Ended
Sep. 23, 2014
Aug. 11, 2014
Sep. 30, 2014
Sep. 23, 2014
Aug. 11, 2014
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]          
Up-front fee     $ 150,000,000    
Potential milestone payment         775,000,000
Profits and losses sharing percentage   35.00%      
Maximum secured loan facility       175,000,000  
Senior notes, effective interest rate       8.50%  
Prepayment of loan percentage of net cash proceeds sale 100.00%        
Development and Manufacturing Milestone Events
         
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]          
Potential milestone payment   75,000,000     75,000,000
Regulatory Approvals
         
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]          
Potential milestone payment   50,000,000     50,000,000
Product Sales Milestones
         
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]          
Potential milestone payment   650,000,000     650,000,000
Sanofi-Aventis Deutschland GmbH
         
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]          
Profits and losses sharing percentage   65.00%      
Collaboration revenue recognized     0    
Deferred revenue     $ 150,000,000