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Facility Agreement - Additional Information (Detail) - USD ($)
$ in Thousands
3 Months Ended 6 Months Ended
Jun. 30, 2015
Mar. 31, 2015
Jun. 30, 2014
Jun. 30, 2015
Jun. 30, 2014
Dec. 31, 2014
Jul. 01, 2013
Debt Instrument [Line Items]              
Short term liability $ 73,757     $ 73,757   $ 72,995  
Interest expense on notes 4,131   $ 2,429 $ 13,753 $ 6,471    
Deerfield              
Debt Instrument [Line Items]              
Principal repayment schedule, start date       Jul. 01, 2016      
Principal repayment schedule, end date       Dec. 09, 2019      
Deerfield | Milestone Rights Liability | Maximum              
Debt Instrument [Line Items]              
Contingent liability for milestone payments             $ 90,000
Deerfield | Senior convertible notes due December 31, 2019              
Debt Instrument [Line Items]              
Debt facility principal amount $ 60,000     $ 60,000      
Senior notes, effective interest rate 9.75%     9.75%      
Deerfield | Senior convertible notes due December 31, 2019 | Less portion of commitment asset              
Debt Instrument [Line Items]              
Debt facility principal amount $ 20,000     $ 20,000      
Senior notes, effective interest rate 8.75%     8.75%      
Deerfield | Senior convertible notes due December 31, 2019 | Less portion of commitment asset | Minimum | Facility Agreement              
Debt Instrument [Line Items]              
Available amount of credit facility under covenant restrictions $ 25,000     $ 25,000      
Deerfield | Senior convertible notes due December 31, 2019 | Milestone Rights Liability              
Debt Instrument [Line Items]              
Short term liability 1,600     1,600     3,200
Long term liability $ 7,300     $ 7,300     $ 13,100
Interest expense on notes   $ 5,800          
Required payment pursuant to the terms of the Milestone Agreement   $ 10,000