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Summary of Carrying Values Estimated Fair Values of Notes and Facility Financing Obligation and Sanofi Loan Facility (Detail) - USD ($) $ in Thousands	Sep. 30, 2015	Dec. 31, 2014
Sanofi-Aventis Deutschland GmbH
Convertible Debt [Line Items]
Carrying value	$ 28,900	$ 3,000
Estimated fair value	28,900	3,000
Senior convertible notes due August 15, 2018
Convertible Debt [Line Items]
Carrying value	27,607
Senior convertible notes due August 15, 2018 | Convertible Debt Securities
Convertible Debt [Line Items]
Carrying value	27,600
Estimated fair value	28,400
Facility financing obligation
Convertible Debt [Line Items]
Carrying value	74,200	73,000
Estimated fair value	$ 78,700	$ 75,100

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- Definition

Convertible Debt [Line Items]

+ References

No definition available.

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Amount of long-term debt before deduction of unamortized discount or premium. Includes, but is not limited to, notes payable, bonds payable, commercial loans, mortgage loans, convertible debt, subordinated debt and other types of debt, with initial maturities beyond one year or the normal operating cycle, if longer.

+ References

Reference 1: http://www.xbrl.org/2003/role/presentationRef



-Publisher FASB



-Name Accounting Standards Codification



-Topic 210



-SubTopic 10



-Section S99



-Paragraph 1



-Subparagraph (SX 210.5-02.22)



-URI http://asc.fasb.org/extlink&oid=6877327&loc=d3e13212-122682



Reference 2: http://www.xbrl.org/2003/role/presentationRef



-Publisher SEC



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-Number 210



-Section 02



-Paragraph 20



-Article 5



Reference 3: http://www.xbrl.org/2003/role/presentationRef



-Publisher SEC



-Name Regulation S-X (SX)



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-Section 03



-Paragraph 16



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Fair value portion of debt instrument payable, including, but not limited to, notes payable and loans payable.

+ References

Reference 1: http://www.xbrl.org/2003/role/presentationRef



-Publisher FASB



-Name Accounting Standards Codification



-Topic 825



-SubTopic 10



-Section 50



-Paragraph 10



-Subparagraph (a)



-URI http://asc.fasb.org/extlink&oid=49121117&loc=d3e13433-108611



Reference 2: http://www.xbrl.org/2003/role/presentationRef



-Publisher FASB



-Name Accounting Standards Codification



-Topic 825



-SubTopic 10



-Section 50



-Paragraph 12



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