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Restructuring Charges - Additional Information (Detail)
$ in Millions
3 Months Ended 9 Months Ended
Sep. 30, 2015
USD ($)
Sep. 30, 2015
USD ($)
Employee
Restructuring Cost and Reserve [Line Items]    
Percentage of workforce reduction   26.00%
Number of employees eliminated | Employee   198
Restructuring charges   $ 3.2
Restructuring liability $ 3.2 $ 3.2
Research and development    
Restructuring Cost and Reserve [Line Items]    
Restructuring charges 2.0  
General and administrative    
Restructuring Cost and Reserve [Line Items]    
Restructuring charges $ 1.2