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Summary of Carrying Values Estimated Fair Values of Notes and Facility Financing Obligation and Sanofi Loan Facility (Detail) - USD ($)
$ in Millions
Mar. 31, 2016
Dec. 31, 2015
Sanofi-Aventis Deutschland GmbH    
Convertible Debt [Line Items]    
Carrying value $ 63.5 $ 44.5
Estimated fair value 48.2 36.5
Senior convertible notes due August 15, 2015 | Convertible Debt Securities    
Convertible Debt [Line Items]    
Carrying value 27.6 27.6
Estimated fair value 21.8 21.3
Facility financing obligation    
Convertible Debt [Line Items]    
Carrying value 75.0 74.6
Estimated fair value $ 79.4 $ 78.4