Condensed Consolidated Statements of Operations - USD ($) shares in Thousands, $ in Thousands	3 Months Ended	6 Months Ended
Jun. 30, 2016	Jun. 30, 2015	Jun. 30, 2016	Jun. 30, 2015
Revenue	$ 0	$ 0	$ 0	$ 0
Operating expenses:
Research and development	4,310	7,737	9,440	17,115
Selling, general and administrative	11,110	10,623	18,460	21,102
Product manufacturing	3,704	5,691	11,236	7,573
Total operating expenses	19,124	24,051	39,136	45,790
Loss from operations	(19,124)	(24,051)	(39,136)	(45,790)
Other (expense) income	(5,959)	(10)	(5,892)	1,403
Interest expense on note payable to principal stockholder	(721)	(721)	(1,443)	(1,435)
Interest expense on notes	(4,181)	(4,131)	(8,401)	(13,753)
Interest income	26	3	41	6
Net loss	$ (29,959)	$ (28,910)	$ (54,831)	$ (59,569)
Net loss per share - basic and diluted	$ (0.07)	$ (0.07)	$ (0.12)	$ (0.15)
Shares used to compute basic and diluted net loss per share	455,305	401,018	442,082	399,972

Total costs of sales and operating expenses for the period.

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Amount of the cost of borrowed funds accounted for as interest expense for debt.

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Amount before accretion (amortization) of purchase discount (premium) of interest income on nonoperating securities.

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The aggregate costs incurred in the production of goods for sale.

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The portion of profit or loss for the period, net of income taxes, which is attributable to the parent.

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Amount of income (expense) related to nonoperating activities, classified as other.

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Expenses recognized resulting from transactions (excluding transactions that are eliminated in consolidated or combined financial statements) with related party.

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The costs incurred in a planned search or critical investigation aimed at discovery of new knowledge with the hope that such knowledge will be useful in developing a new product or service, a new process or technique, or in bringing about a significant improvement to an existing product or process; or to translate research findings or other knowledge into a plan or design for a new product or process or for a significant improvement to an existing product or process whether intended for sale or the entity's use, during the reporting period charged to research and development projects, excluding in-process research and development acquired in a business combination consummated during the period. Excludes software research and development, which has a separate concept.

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Total revenue from sale of goods and services rendered during the reporting period, in the normal course of business, reduced by sales returns and allowances, and sales discounts.

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The aggregate total costs related to selling a firm's product and services, as well as all other general and administrative expenses. Direct selling expenses (for example, credit, warranty, and advertising) are expenses that can be directly linked to the sale of specific products. Indirect selling expenses are expenses that cannot be directly linked to the sale of specific products, for example telephone expenses, Internet, and postal charges. General and administrative expenses include salaries of non-sales personnel, rent, utilities, communication, etc.

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Average number of shares or units issued and outstanding that are used in calculating basic and diluted earnings per share (EPS).

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