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Fair Value of Financial Instruments (Detail) - USD ($)
$ in Millions
Jun. 30, 2016
Dec. 31, 2015
Financial liabilities:    
Financial liabilities fair value $ 197.4 $ 150.6
Sanofi-Aventis Deutschland GmbH    
Financial liabilities:    
Financial liabilities fair value 62.0 36.8
Warrant Liability    
Financial liabilities:    
Financial liabilities fair value 18.1  
Milestone Rights Liability    
Financial liabilities:    
Financial liabilities fair value 15.6 14.4
Senior Convertible Notes | Convertible Debt Securities    
Financial liabilities:    
Financial liabilities fair value 21.8 21.3
Facility financing obligation    
Financial liabilities:    
Financial liabilities fair value 79.9 78.4
Fair Value, Inputs, Level 3    
Financial liabilities:    
Financial liabilities fair value 197.4 150.6
Fair Value, Inputs, Level 3 | Sanofi-Aventis Deutschland GmbH    
Financial liabilities:    
Financial liabilities fair value 62.0 36.5
Fair Value, Inputs, Level 3 | Warrant Liability    
Financial liabilities:    
Financial liabilities fair value 18.1  
Fair Value, Inputs, Level 3 | Milestone Rights Liability    
Financial liabilities:    
Financial liabilities fair value 15.6 14.4
Fair Value, Inputs, Level 3 | Senior Convertible Notes | Convertible Debt Securities    
Financial liabilities:    
Financial liabilities fair value 21.8 21.3
Fair Value, Inputs, Level 3 | Facility financing obligation    
Financial liabilities:    
Financial liabilities fair value $ 79.9 $ 78.4