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Consolidated Balance Sheets - USD ($)
$ in Thousands
Dec. 31, 2016
Dec. 31, 2015
Current assets:    
Cash and cash equivalents $ 22,895 $ 59,074
Accounts receivable 302  
Receivable from Sanofi 30,557 23
Inventory 2,331  
Asset held for sale 16,730  
Deferred costs from commercial product sales 309  
Deferred costs from collaboration   13,539
Prepaid expenses and other current assets 4,364 4,018
Total current assets 77,488 76,654
Property and equipment - net 28,927 48,749
Other assets 648 1,009
Total assets 107,063 126,412
Current liabilities:    
Accounts payable 3,263 15,599
Accrued expenses and other current liabilities 7,937 7,929
Facility financing obligation 71,339 74,582
Deferred revenue - net 3,419  
Deferred payments from collaboration 1,000 140,231
Deferred sales from collaboration   17,503
Recognized loss on purchase commitments - current 5,093 12,475
Total current liabilities 92,051 268,319
Note payable to principal stockholder 49,521 49,521
Accrued interest - note payable to principal stockholder 9,281 6,380
Senior convertible notes 27,635 27,613
Sanofi loan facility and loss share obligation   62,371
Recognized loss on purchase commitments - long term 95,942 53,692
Warrant liability 7,381  
Milestone rights liability and other liabilities 8,845 8,845
Total liabilities 290,656 476,741
Commitments and contingencies (Note 13)
Stockholders' deficit:    
Undesignated preferred stock, $0.01 par value - 10,000,000 shares authorized; no shares issued or outstanding at December 31, 2016 and 2015
Common stock, $0.05 par value - 140,000,000 and 110,000,000 shares authorized at December 31, 2016 and 2015, respectively; 95,680,831 and 85,734,188 shares issued and outstanding at December 31, 2016 and 2015, respectively 4,784 4,287
Additional paid-in capital 2,549,212 2,508,633
Accumulated other comprehensive loss (24) (20)
Accumulated deficit (2,737,565) (2,863,229)
Total stockholders' deficit (183,593) (350,329)
Total liabilities and stockholders' deficit $ 107,063 $ 126,412