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Net Revenue From Collaboration

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Potential Milestone Payments To Be Received

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Proceeds from Option Exercise and License Fees Received

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- Definition

Profit Loss Sharing Agreement Allocation Percentage

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- Definition

Recognition Period for Deferred Revenue

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- Definition

Research And Development Expenses Offset Amount

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- Definition

Termination Date Of License Agreement

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- Definition

Amount, after allowance, receivable from customers, clients, or other third-parties, and receivables classified as other due within one year or the normal operating cycle, if longer.

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Line items represent financial concepts included in a table. These concepts are used to disclose reportable information associated with domain members defined in one or many axes to the table.

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- Definition

Amount, before unamortized (discount) premium and debt issuance costs, of long-term debt. Includes, but is not limited to, notes payable, bonds payable, commercial loans, mortgage loans, convertible debt, subordinated debt and other types of debt.

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- Definition

Decrease for amounts of indebtedness forgiven by the holder of the debt instrument.

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- Definition

Contractual interest rate for funds borrowed, under the debt agreement.

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- Definition

Sum of the carrying amounts of deferred costs that are expected to be recognized as a charge against earnings in periods after one year or beyond the normal operating cycle, if longer.

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Amount of deferred revenue as of balance sheet date. Deferred revenue represents collections of cash or other assets related to a revenue producing activity for which revenue has not yet been recognized. Generally, an entity records deferred revenue when it receives consideration from a customer before achieving certain criteria that must be met for revenue to be recognized in conformity with GAAP.

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- Definition

Difference between the fair value of payments made and the carrying amount of debt which is extinguished prior to maturity.

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Maximum borrowing capacity under the credit facility without consideration of any current restrictions on the amount that could be borrowed or the amounts currently outstanding under the facility.

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- Definition

Carrying value as of the balance sheet date of loans payable (with maturities initially due after one year or beyond the operating cycle if longer), excluding current portion.

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Interest paid other than in cash for example by issuing additional debt securities. As a noncash item, it is added to net income when calculating cash provided by or used in operations using the indirect method.

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The cash outflow for derivative instruments during the period, which are classified as financing activities, excluding those designated as hedging instruments.

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Cash received from collaborators during the current period.

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The cash inflow from a long-term borrowing made from related parties where one party can exercise control or significant influence over another party; including affiliates, owners or officers and their immediate families, pension trusts, and so forth. Alternate caption: Proceeds from Advances from Affiliates.

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Collaborative Arrangement - Additional Information (Detail) - USD ($)					1 Months Ended	3 Months Ended		12 Months Ended
	Dec. 30, 2016	Nov. 09, 2016	Feb. 10, 2016	Jan. 04, 2016	Jan. 31, 2017	Dec. 31, 2016	Sep. 30, 2016	Dec. 31, 2016	Dec. 31, 2015	Sep. 23, 2014
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]
Net revenue from collaboration								$ 171,965,000
Paid-in-kind interest								4,478,000	$ 1,652,000
Gain on extinguishment of debt								72,024,000	(1,049,000)
Balance payment of settlement agreement						$ 30,557,000		30,557,000	23,000
Insulin Put
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]
Net revenue from collaboration								10,200,000
Sanofi-Aventis Deutschland GmbH \| Subsequent Event \| Put Option
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]
Payment for insulin put option					$ 30,600,000
Sanofi-Aventis Deutschland GmbH \| Mortgage Loan
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]
Carrying value									17,900,000
Aventisub LLC
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]
Outstanding loan balance forgiven		$ 72,000,000
Receptor
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]
Nonrefundable payments								400,000
Nonrefundable option exercise and license fee	$ 1,000,000
Reduction in research and development expense								400,000
Deferred revenue - nonrefundable license fee						1,000,000		$ 1,000,000
Deferred revenue recognition period								4 years
License and Collaboration Agreement with Sanofi
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]
Profits and losses sharing percentage								35.00%
Termination date				Apr. 04, 2016
Maximum secured loan facility										$ 175,000,000
Senior notes, effective interest rate										8.50%
Gain on extinguishment of debt		$ 500,000
License and Collaboration Agreement with Sanofi \| Sanofi-Aventis Deutschland GmbH
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]
Deferred revenue - nonrefundable license fee						150,000,000		$ 150,000,000
Profits and losses sharing percentage								65.00%
Milestone receivable						25,000,000		$ 25,000,000
Deferred cost									13,500,000
Net revenue from collaboration						10,200,000	$ 161,800,000	172,000,000
Maximum secured loan facility						175,000,000		175,000,000
Secured loan facility, amount borrowed			$ 17,900,000						44,500,000
Secured loan facility, amount owed									62,400,000
Paid-in-kind interest									1,700,000
Gain on extinguishment of debt						$ 72,000,000
License and Collaboration Agreement with Sanofi \| Sanofi-Aventis Deutschland GmbH \| AFREZZA product sales
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]
Deferred revenue - nonrefundable license fee									17,500,000
Net revenue from collaboration								17,500,000
License and Collaboration Agreement with Sanofi \| Sanofi-Aventis Deutschland GmbH \| Up Front Payment [Member]
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]
Net revenue from collaboration								150,000,000
License and Collaboration Agreement with Sanofi \| Sanofi-Aventis Deutschland GmbH \| Milestone Payment One
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]
Net revenue from collaboration								25,000,000
License and Collaboration Agreement with Sanofi \| Sanofi-Aventis Deutschland GmbH \| Milestone Payment Two
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]
Net revenue from collaboration								25,000,000
License and Collaboration Agreement with Sanofi \| Sanofi-Aventis Deutschland GmbH \| Insulin Put
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]
Net revenue from collaboration								19,400,000
License and Collaboration Agreement with Sanofi \| Sanofi-Aventis Deutschland GmbH \| Operating loss Sharing
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]
Net revenue from collaboration								$ (64,900,000)
Company's total portion of loss sharing									$ 57,700,000