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Commitments and Contingencies - Additional Information (Detail)
€ in Millions
 12 Months Ended 24 Months Ended
Jul. 31, 2014
EUR (€)
Dec. 31, 2016
USD ($)
Dec. 31, 2016
EUR (€)
Dec. 31, 2015
USD ($)
Dec. 31, 2014
USD ($)
Oct. 01, 2018
USD ($)
Jul. 01, 2013
USD ($)
Commitments and Contingencies [Line Items]              
Operating lease rent expenses   $ 373,000   $ 426,000 $ 737,000    
Purchase commitment amount under Insulin Supply Agreement | €     € 93.0        
Supply Agreement expiration period   Dec. 31, 2023 Dec. 31, 2023        
Supply Agreement renewal period   2 years 2 years        
Purchase commitment obligation   $ 116,200,000          
Before Amendment              
Commitments and Contingencies [Line Items]              
Purchase commitment amount under Insulin Supply Agreement | € € 120.1            
Scenario Forecast              
Commitments and Contingencies [Line Items]              
Purchase commitment cancellation fees           $ 3,400,000  
Scenario Forecast | Before Amendment              
Commitments and Contingencies [Line Items]              
Purchase commitment cancellation fees           $ 5,300,000  
Supply Commitment              
Commitments and Contingencies [Line Items]              
Purchase commitment obligation   $ 900,000          
Deerfield | Milestone Rights Liability | Maximum              
Commitments and Contingencies [Line Items]              
Contingent liability for milestone payments             $ 90,000,000