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Description of Business and Significant Accounting Policies - Additional Information (Detail) |  |  |  | 1 Months Ended | 3 Months Ended | 12 Months Ended |  |  |
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Apr. 18, 2017 USD ($) | Mar. 01, 2017 shares | Nov. 09, 2016 USD ($) | Jan. 31, 2017 USD ($) | Mar. 31, 2017 USD ($) Distributor $ / shares shares | Mar. 31, 2016 USD ($) | Dec. 31, 2016 USD ($) Distributor shares | Sep. 30, 2016 shares | Dec. 31, 2015 USD ($) | Sep. 23, 2014
Organization, Consolidation and Presentation of Financial Statements Disclosure [Line Items] |  |  |  |  |  |  |  |  |  |
Net revenue from collaboration |  |  |  |  | $ 63,000 |  |  |  |  |
Accumulated deficit |  |  |  |  | (2,753,889,000) |  | $ (2,737,565,000) |  |  |
Cash and cash equivalents |  |  |  |  | $ 47,978,000 | $ 27,653,000 | $ 22,895,000 |  | $ 59,074,000 |
Stock market bidding requirements, description |  |  |  |  | On September 14, 2016, the Company received notice from the Listing Qualifications Department of the NASDAQ Stock Market indicating that in the previous 30 consecutive business days, the bid price for the common stock closed below the minimum of $1.00 per share required for continued inclusion on the NASDAQ Global Market. |  |  |  |  |
Minimum closing bid requirement, price per share | $ / shares |  |  |  |  | $ 1.00 |  |  |  |  |
Stock split of common stock |  | 0.2 |  |  |  |  |  |  |  |
Common stock, shares authorized | shares |  | 140,000,000 |  |  | 140,000,000 |  | 140,000,000 | 700,000,000 |  |
Reverse stock split, description |  |  |  |  | The Company’s board of directors approved a reverse stock split ratio of 1-for-5. On March 1, 2017, the Company filed with the Secretary of State of the State of Delaware a Certificate of Amendment of the Company’s Amended and Restated Certificate of Incorporation to effect the 1-for-5 reverse stock split of the Company’s outstanding common stock and to reduce the authorized number of shares of the Company’s common stock from 700,000,000 to 140,000,000 shares. The Company’s common stock began trading on the NASDAQ Global Market on a split-adjusted basis when the market opened on March 3, 2017. As a result, all common stock share amounts included in these condensed consolidated financial statements have been retroactively reduced by a factor of five, and all common stock per share amounts have been increased by a factor of five, with the exception of the Company’s common stock par value. |  |  |  |  |
Deferred revenue |  |  |  |  | $ 1,844,000 |  | $ 3,419,000 |  |  |
Net revenue - commercial product sales |  |  |  |  | $ 1,196,000 |  |  |  |  |
Number of wholesale distributors | Distributor |  |  |  |  | 3 |  |  |  |  |
Percentage of product shipments to wholesale distributors |  |  |  |  | 93.00% |  |  |  |  |
Product sales |  |  |  |  | $ 3,009,000 |  |  |  |  |
Cash discount as incentive for prompt payment |  |  |  |  | 2.00% |  |  |  |  |
Deferred revenue from sale of raw insulin |  |  |  |  | $ 0 |  | $ 1,800,000 |  |  |
Number of wholesale distributors accounted for gross accounts receivable | Distributor |  |  |  |  | 3 |  | 3 |  |  |
Allowance for doubtful accounts |  |  |  |  | $ 0 |  | $ 0 |  |  |
Percentage of accounts receivable from major wholesale distributors |  |  |  |  | 92.00% |  | 95.00% |  |  |
Loss on purchase commitments, number of contracts recognized |  |  |  |  | 0 |  | 0 |  |  |
License and Collaboration Agreement with Sanofi |  |  |  |  |  |  |  |  |  |
Organization, Consolidation and Presentation of Financial Statements Disclosure [Line Items] |  |  |  |  |  |  |  |  |  |
Gain on extinguishment of debt |  |  | $ 500,000 |  |  |  |  |  |  |
Senior notes, effective interest rate |  |  |  |  |  |  |  |  |  | 8.50%
Third party logistics |  |  |  |  |  |  |  |  |  |
Organization, Consolidation and Presentation of Financial Statements Disclosure [Line Items] |  |  |  |  |  |  |  |  |  |
Deferred revenue |  |  |  |  | $ 1,800,000 |  | $ 1,600,000 |  |  |
Insulin Put |  |  |  |  |  |  |  |  |  |
Organization, Consolidation and Presentation of Financial Statements Disclosure [Line Items] |  |  |  |  |  |  |  |  |  |
Net revenue from collaboration |  |  |  |  |  |  | 10,200,000 |  |  |
AFREZZA product sales |  |  |  |  |  |  |  |  |  |
Organization, Consolidation and Presentation of Financial Statements Disclosure [Line Items] |  |  |  |  |  |  |  |  |  |
Product sales revenue gross to net adjustments |  |  |  |  | $ 400,000 | 0 |  |  |  |
Product sales revenue gross to net adjustments percentage |  |  |  |  | 27.00% |  |  |  |  |
Product sales |  |  |  |  |  | $ 0 |  |  |  |
Less portion of commitment asset |  |  |  |  |  |  |  |  |  |
Organization, Consolidation and Presentation of Financial Statements Disclosure [Line Items] |  |  |  |  |  |  |  |  |  |
Cash repayment of senior notes under exchange agreement |  |  |  |  | $ 4,000,000 |  |  |  |  |
Conversion of notes to common shares, value |  |  |  |  | $ 1,000,000 |  |  |  |  |
Minimum | AFREZZA product sales |  |  |  |  |  |  |  |  |  |
Organization, Consolidation and Presentation of Financial Statements Disclosure [Line Items] |  |  |  |  |  |  |  |  |  |
Sales return right following product expiration in months |  |  |  |  | 6 months |  |  |  |  |
Maximum | AFREZZA product sales |  |  |  |  |  |  |  |  |  |
Organization, Consolidation and Presentation of Financial Statements Disclosure [Line Items] |  |  |  |  |  |  |  |  |  |
Sales return right following product expiration in months |  |  |  |  | 12 months |  |  |  |  |
Senior convertible notes due December 31, 2019 |  |  |  |  |  |  |  |  |  |
Organization, Consolidation and Presentation of Financial Statements Disclosure [Line Items] |  |  |  |  |  |  |  |  |  |
Conversion of notes to common shares, value |  |  |  |  | $ 5,000,000 |  |  |  |  |
Allowance for Sales Returns |  |  |  |  |  |  |  |  |  |
Organization, Consolidation and Presentation of Financial Statements Disclosure [Line Items] |  |  |  |  |  |  |  |  |  |
Allowance for returns |  |  |  |  | 300,000 |  | 0 |  |  |
Principal stockholder | Loan Arrangement |  |  |  |  |  |  |  |  |  |
Organization, Consolidation and Presentation of Financial Statements Disclosure [Line Items] |  |  |  |  |  |  |  |  |  |
Amount available for future borrowings |  |  |  |  | 30,100,000 |  | 30,100,000 |  |  |
Principal stockholder | Senior convertible notes due December 31, 2019 | Loan Arrangement |  |  |  |  |  |  |  |  |  |
Organization, Consolidation and Presentation of Financial Statements Disclosure [Line Items] |  |  |  |  |  |  |  |  |  |
Amount available for future borrowings |  |  |  |  | 30,100,000 |  |  |  |  |
Sanofi-Aventis Deutschland GmbH | License and Collaboration Agreement with Sanofi |  |  |  |  |  |  |  |  |  |
Organization, Consolidation and Presentation of Financial Statements Disclosure [Line Items] |  |  |  |  |  |  |  |  |  |
Net revenue from collaboration |  |  |  |  | 172,000,000 |  |  |  |  |
Up-front fee |  |  |  |  | 150,000,000 |  |  |  |  |
Sanofi-Aventis Deutschland GmbH | Insulin Put | License and Collaboration Agreement with Sanofi |  |  |  |  |  |  |  |  |  |
Organization, Consolidation and Presentation of Financial Statements Disclosure [Line Items] |  |  |  |  |  |  |  |  |  |
Net revenue from collaboration |  |  |  |  | 19,400,000 |  |  |  |  |
Sanofi-Aventis Deutschland GmbH | AFREZZA product sales | License and Collaboration Agreement with Sanofi |  |  |  |  |  |  |  |  |  |
Organization, Consolidation and Presentation of Financial Statements Disclosure [Line Items] |  |  |  |  |  |  |  |  |  |
Net revenue from collaboration |  |  |  |  | $ 17,500,000 |  |  |  |  |
Sanofi-Aventis Deutschland GmbH | Put Option |  |  |  |  |  |  |  |  |  |
Organization, Consolidation and Presentation of Financial Statements Disclosure [Line Items] |  |  |  |  |  |  |  |  |  |
Payment for insulin put option |  |  |  | $ 30,600,000 |  |  | $ 30,600,000 |  |  |
Aventisub LLC |  |  |  |  |  |  |  |  |  |
Organization, Consolidation and Presentation of Financial Statements Disclosure [Line Items] |  |  |  |  |  |  |  |  |  |
Outstanding loan balance forgive |  |  | $ 72,000,000 |  |  |  |  |  |  |
Deerfield | Senior convertible notes due December 31, 2019 |  |  |  |  |  |  |  |  |  |
Organization, Consolidation and Presentation of Financial Statements Disclosure [Line Items] |  |  |  |  |  |  |  |  |  |
Senior notes, effective interest rate |  |  |  |  | 9.75% |  |  |  |  |
Deerfield | Senior convertible notes due December 31, 2019 | Less portion of commitment asset |  |  |  |  |  |  |  |  |  |
Organization, Consolidation and Presentation of Financial Statements Disclosure [Line Items] |  |  |  |  |  |  |  |  |  |
Senior notes, effective interest rate |  |  |  |  | 8.75% |  |  |  |  |
Deerfield | Senior convertible notes due December 31, 2019 | Less portion of commitment asset | Subsequent Event |  |  |  |  |  |  |  |  |  |
Organization, Consolidation and Presentation of Financial Statements Disclosure [Line Items] |  |  |  |  |  |  |  |  |  |
Cash repayment of senior notes under exchange agreement | $ 4,000,000 |  |  |  |  |  |  |  |  |
Conversion of notes to common shares, value | 1,000,000 |  |  |  |  |  |  |  |  |
Deerfield | Senior convertible notes due December 31, 2019 | Tranche 1 Notes | Subsequent Event |  |  |  |  |  |  |  |  |  |
Organization, Consolidation and Presentation of Financial Statements Disclosure [Line Items] |  |  |  |  |  |  |  |  |  |
Conversion of notes to common shares, value | $ 5,000,000 |  |  |  |  |  |  |  |  |
Deerfield | Senior convertible notes due December 31, 2019 | Minimum | Less portion of commitment asset |  |  |  |  |  |  |  |  |  |
Organization, Consolidation and Presentation of Financial Statements Disclosure [Line Items] |  |  |  |  |  |  |  |  |  |
Available amount of credit facility under covenant restrictions |  |  |  |  | $ 25,000,000 |  |  |  |  |

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