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Fair Value of Financial Instruments (Detail) - USD ($)
$ in Millions
Jun. 30, 2017
Dec. 31, 2016
Financial liabilities:    
Financial liabilities fair value $ 103.0 $ 123.2
Warrant Liability    
Financial liabilities:    
Financial liabilities fair value 0.6 7.4
Milestone Rights Liability    
Financial liabilities:    
Financial liabilities fair value 18.2 18.4
Senior Convertible Notes | Senior Convertible Notes    
Financial liabilities:    
Financial liabilities fair value 24.2 22.9
Facility Financing Obligation    
Financial liabilities:    
Financial liabilities fair value 60.0 74.5
Carrying Value    
Financial liabilities:    
Financial liabilities fair value 94.6 115.2
Carrying Value | Warrant Liability    
Financial liabilities:    
Financial liabilities fair value 0.6 7.4
Carrying Value | Milestone Rights Liability    
Financial liabilities:    
Financial liabilities fair value 8.9 8.9
Carrying Value | Senior Convertible Notes | Senior Convertible Notes    
Financial liabilities:    
Financial liabilities fair value 27.6 27.6
Carrying Value | Facility Financing Obligation    
Financial liabilities:    
Financial liabilities fair value 57.5 71.3
Estimate of Fair Value Measurement | Fair Value, Inputs, Level 3    
Financial liabilities:    
Financial liabilities fair value 103.0 123.2
Estimate of Fair Value Measurement | Fair Value, Inputs, Level 3 | Warrant Liability    
Financial liabilities:    
Financial liabilities fair value 0.6 7.4
Estimate of Fair Value Measurement | Fair Value, Inputs, Level 3 | Milestone Rights Liability    
Financial liabilities:    
Financial liabilities fair value 18.2 18.4
Estimate of Fair Value Measurement | Senior Convertible Notes | Fair Value, Inputs, Level 3 | Senior Convertible Notes    
Financial liabilities:    
Financial liabilities fair value 24.2 22.9
Estimate of Fair Value Measurement | Facility Financing Obligation | Fair Value, Inputs, Level 3    
Financial liabilities:    
Financial liabilities fair value $ 60.0 $ 74.5