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Subsequent Events - Additional Information (Detail) | Oct. 24, 2017 USD ($) | Oct. 23, 2017 USD ($) d $ / shares shares | Oct. 10, 2017 USD ($) $ / shares shares | Aug. 10, 2015 d $ / shares | Sep. 30, 2017 USD ($) shares | Jun. 29, 2017 $ / shares | Apr. 18, 2017 $ / shares | Dec. 31, 2016 USD ($) shares
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Subsequent Event [Line Items] |  |  |  |  |  |  |  |
Common stock, shares issued | shares |  |  |  |  | 104,707,116 |  |  | 95,680,831
5.75% Senior convertible notes due August 15, 2018 |  |  |  |  |  |  |  |
Subsequent Event [Line Items] |  |  |  |  |  |  |  |
Principal amount |  |  |  |  | $ 27,690,000 |  |  | $ 27,690,000
Senior notes, effective interest rate |  |  |  | 5.75% |  |  |  |
No of convertible shares |  |  |  | 29 |  |  |  |
Principal amount per share | $ / shares |  |  |  | $ 1,000 |  |  |  |
Percentage of repurchase price |  |  |  | 100.00% |  |  |  |
Percentage of conversion price equaling stock price |  |  |  | 130.00% |  |  |  |
Number of trading days | d |  |  |  | 20 |  |  |  |
Senior convertible notes due December 31, 2019 |  |  |  |  |  |  |  |
Subsequent Event [Line Items] |  |  |  |  |  |  |  |
Exchange price per share | $ / shares |  |  |  |  |  | $ 1.45 | $ 1.22 |
Principal amount |  |  |  |  | 60,000,000 |  |  | $ 75,000,000
Senior convertible notes due December 31, 2019 | Deerfield |  |  |  |  |  |  |  |
Subsequent Event [Line Items] |  |  |  |  |  |  |  |
Principal amount |  |  |  |  | $ 45,000,000 |  |  |
Senior notes, effective interest rate |  |  |  |  | 9.75% |  |  |
Senior convertible notes due December 31, 2019 | Deerfield | Tranche B Exchange Shares |  |  |  |  |  |  |  |
Subsequent Event [Line Items] |  |  |  |  |  |  |  |
Exchange price per share | $ / shares |  |  |  |  |  |  | $ 1.15 |
Subsequent Event | 5.75% Senior convertible notes due August 15, 2018 |  |  |  |  |  |  |  |
Subsequent Event [Line Items] |  |  |  |  |  |  |  |
Principal amount |  | $ 27,690,000 |  |  |  |  |  |
Subsequent Event | 5.75% Senior convertible notes due October 23, 2021 |  |  |  |  |  |  |  |
Subsequent Event [Line Items] |  |  |  |  |  |  |  |
Principal amount |  | $ 23,690,000 |  |  |  |  |  |
Senior notes, effective interest rate |  | 5.75% |  |  |  |  |  |
Maturity date |  | Oct. 23, 2021 |  |  |  |  |  |
No of convertible shares |  | 194.1748 |  |  |  |  |  |
Principal amount per share | $ / shares |  | $ 1,000 |  |  |  |  |  |
Conversion price of shares | $ / shares |  | $ 5.15 |  |  |  |  |  |
Percentage of repurchase price |  | 100.00% |  |  |  |  |  |
Percentage of conversion price equaling stock price |  | 120.00% |  |  |  |  |  |
Number of trading days | d |  | 10 |  |  |  |  |  |
Consecutive trading days | d |  | 20 |  |  |  |  |  |
Debt instrument, convertible, threshold business days |  | 5 days |  |  |  |  |  |
Subsequent Event | 5.75% Senior convertible notes due October 23, 2021 | Maximum |  |  |  |  |  |  |  |
Subsequent Event [Line Items] |  |  |  |  |  |  |  |
Common stock, shares issued | shares |  | 13,648,300 |  |  |  |  |  |
Subsequent Event | Senior convertible notes due December 31, 2019 | Fourth Amendment to Facility Agreement |  |  |  |  |  |  |  |
Subsequent Event [Line Items] |  |  |  |  |  |  |  |
Deferred payment of credit facility principal amount |  | $ 10,000,000 |  |  |  |  |  |
Subsequent Event | Senior convertible notes due December 31, 2019 | Fourth Amendment to Facility Agreement | Deerfield | Tranche B Exchange Shares |  |  |  |  |  |  |  |
Subsequent Event [Line Items] |  |  |  |  |  |  |  |
Conversion price of shares | $ / shares |  | $ 3.25 |  |  |  |  |  |
Number of trading days | d |  | 3 |  |  |  |  |  |
Subsequent Event | Matthew J. Pfeffer |  |  |  |  |  |  |  |
Subsequent Event [Line Items] |  |  |  |  |  |  |  |
Annual basic salary paid | $ 490,350 |  |  |  |  |  |  |
Severance payment | $ 345,000 |  |  |  |  |  |  |
Subsequent Event | Common Stock |  |  |  |  |  |  |  |
Subsequent Event [Line Items] |  |  |  |  |  |  |  |
Number of shares sold in underwritten public offering | shares |  | 973,236 |  |  |  |  |  |
Subsequent Event | Common Stock | Senior convertible notes due December 31, 2019 | Maximum | Fourth Amendment to Facility Agreement | Deerfield | Tranche B Exchange Shares |  |  |  |  |  |  |  |
Subsequent Event [Line Items] |  |  |  |  |  |  |  |
Number of shares sold in underwritten public offering | shares |  | 4,000,000 |  |  |  |  |  |
Subsequent Event | Purchase Agreements |  |  |  |  |  |  |  |
Subsequent Event [Line Items] |  |  |  |  |  |  |  |
Stock purchase agreements date |  |  | Oct. 10, 2017 |  |  |  |  |
Placement agent fees |  |  | 5.00% |  |  |  |  |
Subsequent Event | Purchase Agreements | Common Stock |  |  |  |  |  |  |  |
Subsequent Event [Line Items] |  |  |  |  |  |  |  |
Number of shares sold in underwritten public offering | shares |  |  | 10,166,600 |  |  |  |  |
Amount of net proceeds from issuance of securities |  |  | $ 57,700,000 |  |  |  |  |
Exchange price per share | $ / shares |  |  | $ 6.00 |  |  |  |  |
Subsequent Event | Charitable Foundation | Common Stock | Director |  |  |  |  |  |  |  |
Subsequent Event [Line Items] |  |  |  |  |  |  |  |
Number of shares sold in underwritten public offering | shares |  |  | 166,600 |  |  |  |  |

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