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Commitments and Contingencies - Additional Information (Detail) € in Millions |  |  | 12 Months Ended | 24 Months Ended |
--- | --- | --- | --- | --- | ---
Nov. 29, 2017 USD ($) | May 05, 2017 USD ($) | Dec. 31, 2017 USD ($) | Dec. 31, 2017 EUR (€) | Dec. 31, 2016 USD ($) | Dec. 31, 2015 USD ($) | Oct. 01, 2018 USD ($) | Jul. 01, 2013 USD ($)
Commitments And Contingencies [Line Items] |  |  |  |  |  |  |  |
Purchase commitment amount under Insulin Supply Agreement | € |  |  |  | € 90.3 |  |  |  |
Purchase commitment cancellation fees |  |  | $ 1,400,000 |  |  |  |  |
Purchase obligation included in accounts payable |  |  | $ 1,600,000 |  |  |  |  |
Supply Agreement expiration period |  |  | Dec. 31, 2023 | Dec. 31, 2023 |  |  |  |
Supply Agreement renewal period |  |  | 2 years | 2 years |  |  |  |
Purchase commitment obligation |  |  | $ 109,300,000 |  |  | $ 116,200,000 |  |
Operating lease rent expenses |  |  | 400,000 |  | $ 400,000 | $ 400,000 |  |
Supply Commitment |  |  |  |  |  |  |  |
Commitments And Contingencies [Line Items] |  |  |  |  |  |  |  |
Purchase commitment obligation |  |  | 400,000 |  |  |  |  |
Scenario Forecast |  |  |  |  |  |  |  |
Commitments And Contingencies [Line Items] |  |  |  |  |  |  |  |
Purchase commitment cancellation fees |  |  |  |  |  |  | $ 3,400,000 |
Scenario Forecast | Before Amendment |  |  |  |  |  |  |  |
Commitments And Contingencies [Line Items] |  |  |  |  |  |  |  |
Purchase commitment cancellation fees |  |  |  |  |  |  | $ 5,300,000 |
Deerfield | Milestone Rights Liability | Maximum |  |  |  |  |  |  |  |
Commitments And Contingencies [Line Items] |  |  |  |  |  |  |  |
Contingent liability for milestone payments |  |  | $ 90,000,000 |  |  |  |  | $ 90,000,000
Russell Ranch Road II LLC [Member] |  |  |  |  |  |  |  |
Commitments And Contingencies [Line Items] |  |  |  |  |  |  |  |
Operating lease rent expenses | $ 35,969 | $ 40,951 |  |  |  |  |  |
Percentage of annual increase in lease payment | 3.00% | 3.00% |  |  |  |  |  |
Lease expiration date | Jan. 31, 2023 | Jan. 31, 2023 |  |  |  |  |  |
Lease renewal option | 5 years | 5 years |  |  |  |  |  |
Maximum reimbursable amount for tenant improvements | $ 56,325 |  |  |  |  |  |  |

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