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Statements of Stockholders' (Deficit) - USD ($) $ in Thousands | Total | TEL AVIV STOCK EXCHANGE | Common Stock | Common Stock TEL AVIV STOCK EXCHANGE | Additional Paid-in Capital | Additional Paid-in Capital TEL AVIV STOCK EXCHANGE | Accumulated Other Comprehensive Income (Loss) | Deficit Accumulated During Development Stage
--- | --- | --- | --- | --- | --- | --- | --- | ---
Beginning Balance at Dec. 31, 2014 | $ (73,770) |  | $ 812 |  | $ 2,420,216 |  | $ (14) | $ (2,494,784)
Beginning Balance (in shares) at Dec. 31, 2014 |  |  | 81,212,000 |  |  |  |  |
Exercise of stock options | 3,258 |  | $ 3 |  | 3,255 |  |  |
Exercise of stock options (in shares) |  |  | 340,000 |  |  |  |  |
Issuance of common shares from the release of restricted stock units | 0 |  | $ 1 |  | (1) |  |  |
Issuance of common shares from the release of restricted stock units (in shares) |  |  | 144,000 |  |  |  |  |
Issuance of common shares pursuant to warrant exercises | 10,123 |  | $ 8 |  | 10,115 |  |  |
Issuance of common shares pursuant to warrant exercises (in shares) |  |  | 843,000 |  |  |  |  |
Issuance of common shares under Employee Stock Purchase Plan | $ 887 |  | $ 1 |  | 886 |  |  |
Issuance of common shares under Employee Stock Purchase Plan (in shares) | 64,245 |  | 54,000 |  |  |  |  |
Stock-based compensation expense | $ 8,725 |  |  |  | 8,725 |  |  |
Restricted stock units taxes paid in cash | (1,856) |  |  |  | (1,856) |  |  |
Capital contribution | 40 |  |  |  | 40 |  |  |
Issuance of common shares pursuant to conversions of certain notes | 7,926 |  | $ 4 |  | 7,922 |  |  |
Issuance of common shares pursuant to conversions of certain notes (in shares) |  |  | 375,000 |  |  |  |  |
Issuance of common stock for lender financing fees | 160 |  |  |  | 160 |  |  |
Issuance of common stock for lender financing fees (in shares) |  |  | 8,000 |  |  |  |  |
Discount on notes-for-stock exchange | 169 |  |  |  | 169 |  |  |
Issuance of common stock | 27,843 | $ 34,710 | $ 18 | $ 28 | 27,825 | $ 34,682 |  |
Issuance of common stock (Shares) |  |  | 1,788,000 | 2,771,000 |  |  |  |
Return of loaned common stock |  |  | $ (18) |  | 18 |  |  |
Return of loaned common stock (in shares) |  |  | (1,800,000) |  |  |  |  |
Issuance of warrant liability | (202) |  |  |  | (202) |  |  |
Reclassification of warrant liability to equity | 109 |  |  |  | 109 |  |  |
Cumulative translation loss | (6) |  |  |  |  |  | (6) |
Net (loss) income | (368,445) |  |  |  |  |  |  | (368,445)
Ending Balance at Dec. 31, 2015 | (350,329) |  | $ 857 |  | 2,512,063 |  | (20) | (2,863,229)
Ending Balance (in shares) at Dec. 31, 2015 |  |  | 85,735,000 |  |  |  |  |
Exercise of stock options | 467 |  | $ 1 |  | 466 |  |  |
Exercise of stock options (in shares) |  |  | 55,000 |  |  |  |  |
Issuance of common shares from the release of restricted stock units | 0 |  | $ 1 |  | (1) |  |  |
Issuance of common shares from the release of restricted stock units (in shares) |  |  | 131,000 |  |  |  |  |
Issuance of common shares under Employee Stock Purchase Plan | $ 426 |  | $ 1 |  | 425 |  |  |
Issuance of common shares under Employee Stock Purchase Plan (in shares) | 104,758 |  | 51,000 |  |  |  |  |
Stock-based compensation expense | $ 5,135 |  |  |  | 5,135 |  |  |
Restricted stock units taxes paid in cash | (165) |  |  |  | (165) |  |  |
Issuance of direct placement - common stock and warrants (value) | 50,000 |  | $ 97 |  | 49,903 |  |  |
Issuance of direct placement - common stock and warrants (shares) |  |  | 9,709,000 |  |  |  |  |
Issuance costs associated with direct placement | (2,037) |  |  |  | (2,037) |  |  |
Issuance of warrant liability | (12,750) |  |  |  | (12,750) |  |  |
Cumulative translation loss | (4) |  |  |  |  |  | (4) |
Net (loss) income | 125,664 |  |  |  |  |  |  | 125,664
Ending Balance at Dec. 31, 2016 | (183,593) |  | $ 957 |  | 2,553,039 |  | (24) | (2,737,565)
Ending Balance (in shares) at Dec. 31, 2016 |  |  | 95,681,000 |  |  |  |  |
Exercise of stock options | $ 24 |  | $ 0 |  | 24 |  |  |
Exercise of stock options (in shares) | 5,300 |  | 5,000 |  |  |  |  |
Issuance of common shares from the release of restricted stock units | $ 1 |  | $ 2 |  | (1) |  |  |
Issuance of common shares from the release of restricted stock units (in shares) |  |  | 135,000 |  |  |  |  |
Issuance of common shares under Employee Stock Purchase Plan | $ 236 |  | $ 1 |  | 235 |  |  |
Issuance of common shares under Employee Stock Purchase Plan (in shares) | 199,578 |  | 103,000 |  |  |  |  |
Stock-based compensation expense | $ 4,847 |  |  |  | 4,847 |  |  |
Restricted stock units taxes paid in cash | (127) |  |  |  | (127) |  |  |
Issuance of common shares pursuant to conversions of certain notes | 21,099 |  | $ 115 |  | 20,984 |  |  |
Issuance of common shares pursuant to conversions of certain notes (in shares) |  |  | 11,496,000 |  |  |  |  |
Issuance of direct placement — common stock | 61,000 |  | $ 102 |  | 60,898 |  |  |
Issuance of direct placement — common stock (shares) |  |  | 10,167,000 |  |  |  |  |
Issuance costs associated with direct placement | (3,310) |  |  |  | (3,310) |  |  |
Issuance of common stock | 564 |  | $ 2 |  | 562 |  |  |
Issuance of common stock (Shares) |  |  | 173,000 |  |  |  |  |
Issuance costs associated with ATM placement | (17) |  |  |  | (17) |  |  |
Reclassification of warrant liability to equity | 1,893 |  | $ 13 |  | 1,880 |  |  |
Reclassification of warrant liability to equity (in shares) |  |  | 1,293,000 |  |  |  |  |
Amortization of shelf fees | (22) |  |  |  | (22) |  |  |
Cumulative translation loss | 6 |  |  |  |  |  | 6 |
Net (loss) income | (117,333) |  |  |  |  |  |  | (117,333)
Ending Balance at Dec. 31, 2017 | $ (214,732) |  | $ 1,192 |  | $ 2,638,992 |  | $ (18) | $ (2,854,898)
Ending Balance (in shares) at Dec. 31, 2017 |  |  | 119,053,000 |  |  |  |  |

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