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Collaboration Arrangements - Additional Information (Detail) - USD ($) $ in Millions |  | 1 Months Ended | 3 Months Ended |
--- | --- | --- | --- | ---
Dec. 30, 2016 | Jan. 31, 2017 | Mar. 31, 2018 | Dec. 31, 2016
Sanofi-Aventis Deutschland GmbH | Put Option |  |  |  |
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items] |  |  |  |
Payment for insulin put option |  | $ 30.6 |  |
Receptor |  |  |  |
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items] |  |  |  |
Nonrefundable option exercise and license fee | $ 1.0 |  |  |
Deferred revenue - nonrefundable license fee |  |  |  | $ 1.0
Deferred revenue recognition period |  |  | 4 years |
Deferred payments from collaboration |  |  | $ 0.7 |
Receptor | Current Liabilities |  |  |  |
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items] |  |  |  |
Deferred payments from collaboration |  |  | $ 0.3 |

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