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Subsequent Events - Additional Information (Detail) - USD ($) $ / shares in Units, $ in Thousands |  |  |  | 3 Months Ended
--- | --- | --- | --- | ---
May 08, 2018 | Apr. 05, 2018 | Oct. 23, 2017 | Mar. 31, 2018
Subsequent Event [Line Items] |  |  |  |
Amount of net proceeds from issuance of securities |  |  |  | $ 634
Common Stock |  |  |  |
Subsequent Event [Line Items] |  |  |  |
Number of shares sold in underwritten public offering |  |  | 973,236 |
Subsequent Event | Cipla Ltd |  |  |  |
Subsequent Event [Line Items] |  |  |  |
Marketing and distribution agreement date | May 08, 2018 |  |  |
Upfront payment received | $ 2,200 |  |  |
Subsequent Event | Purchase Agreements |  |  |  |
Subsequent Event [Line Items] |  |  |  |
Stock purchase agreements date |  | Apr. 05, 2018 |  |
Subsequent Event | Purchase Agreements | Common Stock |  |  |  |
Subsequent Event [Line Items] |  |  |  |
Number of shares sold in underwritten public offering |  | 14,000,000 |  |
Amount of net proceeds from issuance of securities |  | $ 26,300 |  |
Exchange price per share |  | $ 2.00 |  |
Subsequent Event | Purchase Agreements | Warrants |  |  |  |
Subsequent Event [Line Items] |  |  |  |
Warrants to purchase of common stock |  | 14,000,000 |  |
Exercise price of warrants |  | $ 2.38 |  |

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