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Schedule of Adoption of New Revenue Guidance Impact on Condensed Consolidated Statement of Operations (Detail) - USD ($) $ in Thousands | 3 Months Ended
--- | ---
Mar. 31, 2018 | Mar. 31, 2017
Revenues: |  |
Net revenue - commercial product sales | $ 3,402 | $ 1,196
Expenses: |  |
Cost of goods sold | 4,008 | 2,548
Net loss | (30,385) | $ (16,324)
Adjustments | Accounting Standards Update 2014-09 |  |
Revenues: |  |
Net revenue - commercial product sales | 589 |
Expenses: |  |
Cost of goods sold | 44 |
Net loss | 545 |
Balances Without Adoption of Topic 606 | Accounting Standards Update 2014-09 |  |
Revenues: |  |
Net revenue - commercial product sales | 3,991 |
Expenses: |  |
Cost of goods sold | 4,052 |
Net loss | $ (29,840) |

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