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Borrowings - Facility Financing Obligation (2019 Notes and Tranche B Notes) - Additional Information (Detail)
1 Months Ended 3 Months Ended 6 Months Ended
Jul. 12, 2018
USD ($)
$ / shares
shares
Jun. 08, 2018
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$ / shares
shares
Mar. 12, 2018
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shares
Mar. 06, 2018
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d
$ / shares
shares
Jan. 18, 2018
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d
$ / shares
shares
Jan. 15, 2018
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Nov. 06, 2017
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$ / shares
shares
Oct. 23, 2017
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d
$ / shares
shares
Jun. 29, 2017
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$ / shares
shares
Apr. 18, 2017
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$ / shares
shares
Aug. 31, 2018
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Feb. 28, 2015
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Jun. 30, 2018
USD ($)
$ / shares
shares
Jun. 30, 2017
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Jun. 30, 2018
USD ($)
$ / shares
shares
Jun. 30, 2017
USD ($)
Jun. 07, 2018
USD ($)
$ / shares
Mar. 09, 2018
$ / shares
Dec. 31, 2017
USD ($)
$ / shares
shares
Sep. 30, 2017
USD ($)
Jul. 01, 2013
USD ($)
Debt Instrument [Line Items]                                          
Principal amount                         $ 129,200,000   $ 129,200,000            
Gain (Loss) on extinguishment of debt                         772,000 $ (830,000) (53,000) $ (830,000)          
Cash and cash equivalents                         $ 26,178,000   $ 26,178,000       $ 43,946,000    
Common stock, shares issued | shares                         145,619,293   145,619,293       119,053,414    
Common stock, par value | $ / shares                         $ 0.01   $ 0.01       $ 0.01    
Milestone rights liability, noncurrent                         $ 7,201,000   $ 7,201,000       $ 7,201,000    
Interest expense on notes                       $ 5,800,000 1,709,000 $ 2,422,000 3,503,000 $ 5,128,000          
Required payment pursuant to the terms of the Milestone Agreement                       $ 10,000,000                  
Common Stock                                          
Debt Instrument [Line Items]                                          
Number of shares sold in underwritten public offering | shares               973,236                          
Tranche B Notes                                          
Debt Instrument [Line Items]                                          
Principal amount                         $ 7,000,000   $ 7,000,000            
Senior notes, effective interest rate                         8.75%   8.75%            
Senior convertible notes due December 31, 2019                                          
Debt Instrument [Line Items]                                          
Principal amount                         $ 32,000,000   $ 32,000,000            
Conversion of notes to common shares, value       $ 1,300,000                                  
Exchange price per share | $ / shares       $ 2.83         $ 1.45 $ 1.22                      
Gain (Loss) on extinguishment of debt                 $ (500,000)                        
Cash repayment                   $ 4,000,000                      
Debt extinguishment amount                 5,000,000                        
Debt discount and issuance costs                 300,000                        
Number of trading days | d       3                                  
Senior notes, effective interest rate                         9.75%   9.75%            
Senior convertible notes due December 31, 2019 | Common Stock                                          
Debt Instrument [Line Items]                                          
Conversion Option, shares | shares       441,618                                  
Senior convertible notes due December 31, 2019 | Tranche B Notes                                          
Debt Instrument [Line Items]                                          
Principal amount                         $ 39,000,000   $ 39,000,000       54,407,000    
Gain (Loss) on extinguishment of debt                   (300,000)                      
2019 Notes and Tranche B Notes | Fourth Amendment to Facility Agreement                                          
Debt Instrument [Line Items]                                          
Deferred payment of credit facility principal amount               $ 10,000,000                          
Deerfield | Tranche B Notes                                          
Debt Instrument [Line Items]                                          
Principal amount                         20,000,000   20,000,000            
Deerfield | Tranche B Exchange Shares                                          
Debt Instrument [Line Items]                                          
Conversion of notes to common shares, value     $ 5,000,000                                    
Conversion Option, shares | shares     1,838,236                                    
Exchange price per share | $ / shares                                   $ 2.72      
Deerfield | Milestone Rights Liability                                          
Debt Instrument [Line Items]                                          
Contingent liability for milestone payments, remain payable amount                         75,000,000   75,000,000           $ 75,000,000
Deerfield | Milestone Rights Liability | Maximum                                          
Debt Instrument [Line Items]                                          
Contingent liability for milestone payments                         90,000,000   90,000,000           $ 90,000,000
Deerfield | Senior convertible notes due December 31, 2019                                          
Debt Instrument [Line Items]                                          
Principal amount                         120,000,000   120,000,000            
Milestone rights liability, noncurrent                         7,200,000   7,200,000       7,200,000    
Remaining milestone rights liability                         $ 8,800,000   $ 8,800,000       8,800,000    
Senior notes, effective interest rate                         9.75%   9.75%            
Deerfield | Senior convertible notes due December 31, 2019 | Accrued Expenses and Other Current Liabilities                                          
Debt Instrument [Line Items]                                          
Milestone rights liability, current                         $ 1,600,000   $ 1,600,000       $ 1,600,000    
Deerfield | Senior convertible notes due December 31, 2019 | Fifth Amendment to Facility Agreement                                          
Debt Instrument [Line Items]                                          
Deferred payment of credit facility principal amount           $ 4,400,000                              
Deerfield | Senior convertible notes due December 31, 2019 | Sixth Amendment to Facility Agreement                                          
Debt Instrument [Line Items]                                          
Conversion of notes to common shares, value         $ 3,200,000                                
Exchange price per share | $ / shares         $ 2.49                                
Deferred payment of credit facility principal amount         $ 1,300,000                                
Common stock, shares issued | shares         1,267,972                                
Common stock, par value | $ / shares         $ 0.01                                
Deerfield | Senior convertible notes due December 31, 2019 | Seventh Amendment to Facility Agreement                                          
Debt Instrument [Line Items]                                          
Conversion Option, shares | shares   3,061,224                                      
Exchange price per share | $ / shares   $ 1.96                                      
Cash and cash equivalents   $ 20,000,000                                      
Deerfield | Senior convertible notes due December 31, 2019 | Seventh Amendment to Facility Agreement | 2019 Notes Due And Payable On July 1, 2018                                          
Debt Instrument [Line Items]                                          
Principal amount   5,000,000                                      
Conversion of notes to common shares, value   $ 3,000,000                                      
Deerfield | Senior convertible notes due December 31, 2019 | Facility Agreement Third Amendment                                          
Debt Instrument [Line Items]                                          
Cash repayment of senior notes under exchange agreement                 10,000,000                        
Conversion of notes to common shares, value                 $ 5,000,000                        
Conversion Option, shares | shares                 3,584,230                        
Exchange price per share | $ / shares                 $ 1.395                        
Cash and cash equivalents                 $ 10,000,000                        
Deerfield | Senior convertible notes due December 31, 2019 | Facility Agreement Eighth Amendment | Subsequent Event                                          
Debt Instrument [Line Items]                                          
Common stock, shares issued | shares 7,367,839                                        
Deerfield | Senior convertible notes due December 31, 2019 | Minimum | Seventh Amendment to Facility Agreement                                          
Debt Instrument [Line Items]                                          
Cash and cash equivalents                                 $ 25,000,000        
Deerfield | Senior convertible notes due December 31, 2019 | Minimum | Facility Agreement Third Amendment                                          
Debt Instrument [Line Items]                                          
Cash and cash equivalents                 $ 25,000,000                     $ 10,000,000  
Deerfield | Senior convertible notes due December 31, 2019 | Minimum | Facility Agreement Eighth Amendment | Common Stock | Subsequent Event                                          
Debt Instrument [Line Items]                                          
Conversion price of shares | $ / shares $ 1.80                                        
Deerfield | Senior convertible notes due December 31, 2019 | Maximum | Facility Agreement Eighth Amendment | Common Stock | Subsequent Event                                          
Debt Instrument [Line Items]                                          
Conversion Option, shares | shares 5,750,000                                        
Conversion price of shares | $ / shares $ 2.01                                        
Deerfield | Senior convertible notes due December 31, 2019 | Tranche B Notes                                          
Debt Instrument [Line Items]                                          
Cash repayment of senior notes under exchange agreement                   4,000,000                      
Conversion of notes to common shares, value                   $ 1,000,000                      
Senior notes, effective interest rate                         8.75%   8.75%            
Deerfield | Senior convertible notes due December 31, 2019 | Tranche B Exchange Shares                                          
Debt Instrument [Line Items]                                          
Conversion Option, shares | shares                   869,565                      
Exchange price per share | $ / shares                   $ 1.15                      
Deerfield | Senior convertible notes due December 31, 2019 | Tranche B Exchange Shares | Fourth Amendment to Facility Agreement                                          
Debt Instrument [Line Items]                                          
Conversion of notes to common shares, value             $ 5,600,000                            
Conversion Option, shares | shares             1,720,846                            
Conversion price of shares | $ / shares             $ 3.25                            
Deerfield | Senior convertible notes due December 31, 2019 | Tranche B Exchange Shares | Sixth Amendment to Facility Agreement                                          
Debt Instrument [Line Items]                                          
Number of trading days | d         3                                
Conversion price of shares | $ / shares         $ 2.75                                
Deerfield | Senior convertible notes due December 31, 2019 | Tranche B Exchange Shares | Seventh Amendment to Facility Agreement                                          
Debt Instrument [Line Items]                                          
Conversion price of shares | $ / shares   $ 2.01                             $ 2.75        
Deerfield | Senior convertible notes due December 31, 2019 | Tranche B Exchange Shares | Seventh Amendment to Facility Agreement | Tranche B Notes Due and Payable on December 31, 2019                                          
Debt Instrument [Line Items]                                          
Conversion of notes to common shares, value   $ 3,000,000                                      
Deerfield | Senior convertible notes due December 31, 2019 | Tranche B Exchange Shares | Common Stock | Sixth Amendment to Facility Agreement                                          
Debt Instrument [Line Items]                                          
Number of shares sold in underwritten public offering | shares         10,000,000                                
Deerfield | Senior convertible notes due December 31, 2019 | Tranche B Exchange Shares | Maximum | Seventh Amendment to Facility Agreement                                          
Debt Instrument [Line Items]                                          
Conversion Option, shares | shares   9,558,382                                      
Deerfield | Senior convertible notes due December 31, 2019 | Tranche 1 Notes                                          
Debt Instrument [Line Items]                                          
Conversion of notes to common shares, value                   $ 5,000,000                      
Conversion Option, shares | shares                   4,347,826                      
Deerfield | Senior convertible notes due December 31, 2019 | Tranche 4 Notes | Facility Agreement Eighth Amendment | Scenario Forecast                                          
Debt Instrument [Line Items]                                          
Cash repayment of senior notes under exchange agreement                     $ 3,000,000                    
Deerfield | Senior convertible notes due December 31, 2019 | Tranche 4 Notes | Facility Agreement Eighth Amendment | Notes Due and Payable on December 31, 2019 | Subsequent Event                                          
Debt Instrument [Line Items]                                          
Principal amount $ 5,000,000                                        
Conversion of notes to common shares, value 3,000,000                                        
Deerfield | 2019 Notes and Tranche B Notes | Tranche B Exchange Shares | Fourth Amendment to Facility Agreement                                          
Debt Instrument [Line Items]                                          
Number of trading days | d               3                          
Conversion price of shares | $ / shares               $ 3.25                          
Deerfield | 2019 Notes and Tranche B Notes | Tranche B Exchange Shares | Maximum | Common Stock | Fourth Amendment to Facility Agreement                                          
Debt Instrument [Line Items]                                          
Number of shares sold in underwritten public offering | shares               4,000,000                          
Deerfield | 9.75% Senior Convertible Notes Due 2019 | Tranche 4 Notes | Facility Agreement Eighth Amendment | Notes Due and Payable on July 18, 2018 | Subsequent Event                                          
Debt Instrument [Line Items]                                          
Principal amount 10,000,000                                        
Conversion of notes to common shares, value $ 7,000,000                                        
Senior notes, effective interest rate 9.75%                                        
Deerfield | 8.75% Senior Convertible Notes Due 2019 | Facility Agreement Eighth Amendment | Notes Due and Payable on December 31, 2019 | Subsequent Event                                          
Debt Instrument [Line Items]                                          
Principal amount $ 2,000,000                                        
Conversion of notes to common shares, value $ 2,000,000                                        
Senior notes, effective interest rate 8.75%