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Commitments and Contingencies - Additional Information (Detail) $ / shares in Units, € in Millions |  |  |  |  |  | 3 Months Ended | 9 Months Ended | 24 Months Ended |  |  |  |
--- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | ---
Apr. 05, 2018 USD ($) $ / shares shares | Apr. 02, 2018 EUR (€) | Nov. 29, 2017 USD ($) | Oct. 23, 2017 shares | May 05, 2017 USD ($) | Sep. 30, 2018 USD ($) | Jun. 30, 2018 USD ($) | Sep. 30, 2017 USD ($) | Sep. 30, 2018 USD ($) Vehicle | Sep. 30, 2018 EUR (€) Vehicle | Sep. 30, 2017 USD ($) | Oct. 01, 2018 USD ($) | Sep. 30, 2018 EUR (€) | Mar. 08, 2018 USD ($) | Dec. 31, 2017 USD ($) | Jul. 01, 2013 USD ($)
Commitments And Contingencies [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Purchase commitment amount under Insulin Supply Agreement | € |  |  |  |  |  |  |  |  |  | € 85.8 |  |  |  |  |  |
Purchase obligation included in accounts payable |  |  |  |  |  |  |  |  |  |  |  |  |  |  | $ 1,600,000 |
Supply Agreement expiration period |  |  |  |  |  |  |  |  | Dec. 31, 2023 | Dec. 31, 2023 |  |  |  |  |  |
Supply Agreement renewal period |  |  |  |  |  |  |  |  | 2 years | 2 years |  |  |  |  |  |
Purchase requirement amount for remaining current year | € |  |  |  |  |  |  |  |  |  |  |  |  | € 4.4 |  |  |
Realized currency loss |  |  |  |  |  | $ (728,000) |  | $ 3,684,000 | $ (3,107,000) |  | $ 12,077,000 |  |  |  |  |
Amount of net proceeds from issuance of securities |  |  |  |  |  |  |  |  | 819,000 |  |  |  |  |  |  |
Operating lease rent expenses |  |  |  |  |  | $ 100,000 |  |  | $ 400,000 |  |  |  |  |  |  |
Lease Agreement with Enterprise | Vehicle Leases |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Commitments And Contingencies [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Number of vehicle leases | Vehicle |  |  |  |  |  |  |  |  | 100 | 100 |  |  |  |  |  |
Operating lease rent expenses |  |  |  |  |  |  |  |  | $ 54,000 |  |  |  |  |  |  |
Lease commencement period |  |  |  |  |  |  |  |  | second quarter of 2018 | second quarter of 2018 |  |  |  |  |  |
Lease expiration period |  |  |  |  |  | 48 months |  |  | 48 months |  |  |  | 48 months |  |  |
Common Stock |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Commitments And Contingencies [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Number of shares sold in underwritten public offering | shares |  |  |  | 973,236 |  |  |  |  |  |  |  |  |  |  |  |
Purchase Agreements |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Commitments And Contingencies [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Stock purchase agreements date | Apr. 05, 2018 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Purchase Agreements | Common Stock |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Commitments And Contingencies [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Number of shares sold in underwritten public offering | shares | 14,000,000 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Amount of net proceeds from issuance of securities | $ 26,400,000 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Exchange price per share | $ / shares | $ 2.00 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Purchase Agreements | Warrants |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Commitments And Contingencies [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Warrants to purchase of common stock | shares | 14,000,000 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Exercise price of warrants | $ / shares | $ 2.38 |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Supply Commitment |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Commitments And Contingencies [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Purchase commitment obligation |  |  |  |  |  | $ 100,000 |  |  | $ 100,000 |  |  |  |  |  |  |
Foreign Currency Hedging Transaction |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Commitments And Contingencies [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Purchase requirement amount for remaining current year | € |  | € 4.4 |  |  |  |  |  |  |  |  |  |  |  |  |  |
Foreign currency hedging transaction renewable period |  | 90 days |  |  |  |  |  |  |  |  |  |  |  |  |  |
Foreign Currency Hedging Transaction | Cost of Goods Sold |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Commitments And Contingencies [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Realized currency loss |  |  |  |  |  | 100,000 | $ 500,000 |  |  |  |  |  |  |  |  |
Scenario Forecast |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Commitments And Contingencies [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Purchase commitment cancellation fees |  |  |  |  |  |  |  |  |  |  |  | $ 3,400,000 |  |  |  |
Scenario Forecast | Before Amendment |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Commitments And Contingencies [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Purchase commitment cancellation fees |  |  |  |  |  |  |  |  |  |  |  | $ 5,300,000 |  |  |  |
Standby Letter of Credit | Vehicle Leases |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Commitments And Contingencies [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Maximum borrowing capacity |  |  |  |  |  |  |  |  |  |  |  |  |  | $ 500,000 |  |
Collateralized amount under letter of credit |  |  |  |  |  |  |  |  |  |  |  |  |  | $ 500,000 |  |
Amount drawn down on letter of credit |  |  |  |  |  | 0 |  |  | 0 |  |  |  |  |  |  |
Deerfield | Milestone Rights Liability |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Commitments And Contingencies [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Contingent liability for milestone payments, remain payable amount |  |  |  |  |  | 75,000,000 |  |  | 75,000,000 |  |  |  |  |  |  | $ 75,000,000
Deerfield | Milestone Rights Liability | Maximum |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Commitments And Contingencies [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Contingent liability for milestone payments |  |  |  |  |  | $ 90,000,000 |  |  | $ 90,000,000 |  |  |  |  |  |  | $ 90,000,000
Russell Ranch Road II LLC |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Commitments And Contingencies [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |
Operating lease rent expenses |  |  | $ 35,969 |  | $ 40,951 |  |  |  |  |  |  |  |  |  |  |
Percentage of annual increase in lease payment |  |  | 3.00% |  | 3.00% |  |  |  |  |  |  |  |  |  |  |
Lease expiration date |  |  | Jan. 31, 2023 |  | Jan. 31, 2023 |  |  |  |  |  |  |  |  |  |  |
Lease renewal option |  |  | 5 years |  | 5 years |  |  |  |  |  |  |  |  |  |  |
Maximum reimbursable amount for tenant improvements |  |  | $ 56,325 |  |  |  |  |  |  |  |  |  |  |  |  |

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