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Summary of Significant Accounting Policies (Tables) - Accounting Standards Update 2014-09 | 12 Months Ended
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Dec. 31, 2018
Summary Of Significant Accounting Policies [Line Items] |
Schedule of Cumulative Effect of Changes to Consolidated Balance Sheet for Adoption of New Revenue Guidance | The cumulative effect of the changes made to the consolidated January 1, 2018 balance sheet for the adoption of the new revenue guidance was as follows (in thousands):
|  | Balance at December 31, 2017 |  |  | Adjustments due to new revenue guidance |  |  |  | Balance at January 1, 2018 |
Assets |  |  |  |  |  |  |  |  |  |  |  |  |
Accounts receivable, net |  | $ | 2,789 |  |  | $ | (111 | ) | (1) |  | $ | 2,678 |
Deferred costs from commercial product sales |  |  | 405 |  |  |  | (405 | ) | (2) |  |  | — |
Liabilities |  |  |  |  |  |  |  |  |  |  |  |  |
Accrued expenses and other current liabilities |  | $ | 12,449 |  |  | $ | 649 |  | (3) |  | $ | 13,098 |
Deferred revenue, net |  |  | 3,038 |  |  |  | (3,038 | ) | (4) |  |  | — |
Equity |  |  |  |  |  |  |  |  |  |  |  |  |
Accumulated deficit |  | $ | (2,854,898 | ) |  | $ | 1,873 |  | (5) |  | $ | (2,853,025 | )
(1) | To establish a reserve for product returns
(2) | To eliminate deferred costs from commercial product sales previously required by the sell-through method
(3) | To record additional accrual for estimated voucher payments related to inventory remaining in the distribution channel at January 1, 2018
(4) | To eliminate deferred revenue previously required by the sell-through method
(5) | To record the net impact of (1)-(4) in opening accumulated deficit
Schedule of Adoption of New Revenue Guidance Impact on Financial Statements | In accordance with the new revenue guidance, the disclosure of the impact of adoption on the consolidated balance sheet consolidated statement of operations and cash flows was as follows (in thousands):
Consolidated Balance Sheet |  |  |  |  |  |  |  |  |  |  |  |
|  | For the year December 31, 2018 |
|  | As Reported |  |  | Adjustments |  |  | Balances without adoption of Topic 606 |
Assets |  |  |  |  |  |  |  |  |  |  |  |
Accounts receivable, net |  | $ | 4,017 |  |  | $ | 314 |  |  | $ | 4,331 |
Deferred costs from commercial product sales |  |  | — |  |  |  | 875 |  |  |  | 875 |
Liabilities |  |  |  |  |  |  |  |  |  |  |  |
Accrued expenses and other current liabilities |  | $ | 15,022 |  |  | $ | (751 | ) |  | $ | 14,271 |
Deferred revenue, net |  |  | — |  |  |  | 3,937 |  |  |  | 3,937 |
Equity |  |  |  |  |  |  |  |  |  |  |  |
Accumulated deficit |  | $ | (2,940,000 | ) |  | $ | (1,997 | ) |  | $ | (2,941,997 | )
Consolidated Statement of Operations |  |  |  |  |  |  |  |  |  |  |  |
|  | For the year December 31, 2018 |
|  | As Reported |  |  | Adjustments |  |  | Balances without adoption of Topic 606 |
Revenue |  |  |  |  |  |  |  |  |  |  |  |
Net revenue - commercial product sales |  | $ | 17,276 |  |  | $ | (486 | ) |  | $ | 16,790 |
Expenses |  |  |  |  |  |  |  |  |  |  |  |
Cost of goods sold |  | $ | 19,402 |  |  | $ | (754 | ) |  | $ | 18,648 |
Net loss |  |  | (86,975 | ) |  |  | (267 | ) |  |  | (87,242 | )
|  | For the year ended December 31, 2018 |
|  | As Reported |  |  | Adjustments |  |  | Balances without adoption of Topic 606 |
Cash Flows from Operating Activities |  |  |  |  |  |  |  |  |  |  |  |
Net loss |  | $ | (86,975 | ) |  | $ | (267 | ) |  | $ | (87,242 | )
Change in: |  |  |  |  |  |  |  |  |  |  |  |
Accounts receivable, net |  |  | (1,339 | ) |  |  | 2,567 |  |  |  | 1,228 |
Deferred costs from commercial product sales |  |  | — |  |  |  | 470 |  |  |  | 470 |
Accrued expenses and other current liabilities |  |  | 2,249 |  |  |  | (751 | ) |  |  | 1,498 |
Deferred revenue, net |  |  | — |  |  |  | (899 | ) |  |  | (899 | )
Cash (used in) provided by operating activities |  |  | (37,731 | ) |  |  | 1,120 |  |  |  | (36,611 | )

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