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Potential Dilutive Securities Outstanding that are Considered Antidilutive (Detail) - shares | 12 Months Ended
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Dec. 31, 2018 | Dec. 31, 2017 | Dec. 31, 2016
Antidilutive Securities Excluded From Computation Of Earnings Per Share [Line Items] |  |  |
Anti-dilutive securities excluded from computation of earnings per share | 78,212,465 | 15,268,444 | 16,831,953
Vesting of Restricted Stock Units |  |  |
Antidilutive Securities Excluded From Computation Of Earnings Per Share [Line Items] |  |  |
Anti-dilutive securities excluded from computation of earnings per share | 691,266 | 1,135,216 | 702,867
Employee Stock Purchase Plan |  |  |
Antidilutive Securities Excluded From Computation Of Earnings Per Share [Line Items] |  |  |
Anti-dilutive securities excluded from computation of earnings per share | 307,395 | 136,660 | 43,672
Exercise of Common Stock Options |  |  |
Antidilutive Securities Excluded From Computation Of Earnings Per Share [Line Items] |  |  |
Anti-dilutive securities excluded from computation of earnings per share | 10,976,118 | 7,089,440 | 5,530,256
Conversion of Convertible Notes into Common Stock |  |  |
Antidilutive Securities Excluded From Computation Of Earnings Per Share [Line Items] |  |  |
Anti-dilutive securities excluded from computation of earnings per share | 3,629,627 | 6,875,272 | 814,561
Conversion of Convertible Related Party Notes into Common Stock |  |  |
Antidilutive Securities Excluded From Computation Of Earnings Per Share [Line Items] |  |  |
Anti-dilutive securities excluded from computation of earnings per share | 21,909,541 |  |
Exercise of Common Stock Warrants |  |  |
Antidilutive Securities Excluded From Computation Of Earnings Per Share [Line Items] |  |  |
Anti-dilutive securities excluded from computation of earnings per share | 31,851 | 31,856 | 9,740,597
Exercise of Warrants Associated with Public Offering |  |  |
Antidilutive Securities Excluded From Computation Of Earnings Per Share [Line Items] |  |  |
Anti-dilutive securities excluded from computation of earnings per share | 26,666,667 |  |
Exercise of Warrants Associated with Direct Placement |  |  |
Antidilutive Securities Excluded From Computation Of Earnings Per Share [Line Items] |  |  |
Anti-dilutive securities excluded from computation of earnings per share | 14,000,000 |  |

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- Definition Securities (including those issuable pursuant to contingent stock agreements) that could potentially dilute basic earnings per share (EPS) or earnings per unit (EPU) in the future that were not included in the computation of diluted EPS or EPU because to do so would increase EPS or EPU amounts or decrease loss per share or unit amounts for the period presented. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 260 -SubTopic 10 -Section 50 -Paragraph 1 -Subparagraph (c) -URI http://asc.fasb.org/extlink&oid=6371337&loc=d3e3550-109257 + Details
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- Definition Line items represent financial concepts included in a table. These concepts are used to disclose reportable information associated with domain members defined in one or many axes to the table. + References No definition available. + Details
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