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Description of Business - Additional Information (Detail) - USD ($)
Dec. 31, 2018
Oct. 31, 2018
Sep. 26, 2018
Jun. 08, 2018
Jun. 07, 2018
Dec. 31, 2017
Jun. 29, 2017
Organization Consolidation And Presentation Of Financial Statements Disclosure [Line Items]              
Accumulated deficit $ (2,940,000,000)         $ (2,854,898,000)  
Cash and cash equivalents 71,157,000         43,946,000  
Restricted cash 527,000         4,409,000  
Principal amount of outstanding borrowings $ 101,700,000            
2019 notes              
Organization Consolidation And Presentation Of Financial Statements Disclosure [Line Items]              
Senior notes, effective interest rate 9.75%            
Principal amount of outstanding borrowings $ 9,000,000         39,400,000  
Tranche B notes              
Organization Consolidation And Presentation Of Financial Statements Disclosure [Line Items]              
Senior notes, effective interest rate 8.75%            
Principal amount of outstanding borrowings $ 2,500,000         $ 15,000,000  
Deerfield              
Organization Consolidation And Presentation Of Financial Statements Disclosure [Line Items]              
Cash and cash equivalents       $ 20,000,000      
Available amount of credit facility under covenant restrictions for each quarter end after current fiscal $ 25,000,000   $ 25,000,000        
Deerfield | 2019 notes              
Organization Consolidation And Presentation Of Financial Statements Disclosure [Line Items]              
Cash and cash equivalents             $ 10,000,000
Senior notes, effective interest rate 9.75%            
Deerfield | Tranche B notes              
Organization Consolidation And Presentation Of Financial Statements Disclosure [Line Items]              
Senior notes, effective interest rate 8.75%            
Minimum | Deerfield              
Organization Consolidation And Presentation Of Financial Statements Disclosure [Line Items]              
Cash and cash equivalents         $ 25,000,000    
Available amount of credit facility under covenant restrictions $ 20,000,000 $ 20,000,000          
Minimum | Deerfield | 2019 notes              
Organization Consolidation And Presentation Of Financial Statements Disclosure [Line Items]              
Cash and cash equivalents $ 10,000,000           $ 25,000,000