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Description of Business and Significant Accounting Policies - Additional Information (Detail) € in Millions | 3 Months Ended | 12 Months Ended |  |  |
--- | --- | --- | --- | --- | ---
Mar. 31, 2019 USD ($) Contract | Dec. 31, 2018 USD ($) Contract | Mar. 31, 2019 EUR (€) | Jan. 01, 2019 USD ($) | Jul. 01, 2013 USD ($)
Organization, Consolidation and Presentation of Financial Statements Disclosure [Line Items] |  |  |  |  |
Accumulated deficit | $ (2,954,883,000) | $ (2,940,000,000) |  |  |
Cash and cash equivalents | 34,530,000 | $ 71,157,000 |  |  |
Short-term investments | 24,764,000 |  |  |  |
Principal amount of outstanding borrowings | 101,700,000 |  |  |  |
Loss on purchase commitments | € |  |  | € 84.1 |  |
(“ASC”) Topic 842 – Leases |  |  |  |  |
Organization, Consolidation and Presentation of Financial Statements Disclosure [Line Items] |  |  |  |  |
Increase in total assets and total liabilities |  |  |  | $ 5,200,000 |
Short-term Investments |  |  |  |  |
Organization, Consolidation and Presentation of Financial Statements Disclosure [Line Items] |  |  |  |  |
Gain (loss) on investments | 0 |  |  |  |
Insulin |  |  |  |  |
Organization, Consolidation and Presentation of Financial Statements Disclosure [Line Items] |  |  |  |  |
Loss on purchase commitments | $ 94,400,000 |  |  |  |
Loss on purchase commitments, number of new contracts recognized | Contract | 0 | 0 |  |  |
Minimum | AFREZZA product sales |  |  |  |  |
Organization, Consolidation and Presentation of Financial Statements Disclosure [Line Items] |  |  |  |  |
Sales return right following product expiration in months | 6 months |  |  |  |
Maximum | AFREZZA product sales |  |  |  |  |
Organization, Consolidation and Presentation of Financial Statements Disclosure [Line Items] |  |  |  |  |
Sales return right following product expiration in months | 12 months |  |  |  |
2019 notes |  |  |  |  |
Organization, Consolidation and Presentation of Financial Statements Disclosure [Line Items] |  |  |  |  |
Senior notes, effective interest rate | 9.75% |  | 9.75% |  |
Principal amount of outstanding borrowings | $ 9,000,000 |  |  |  |
Tranche B notes |  |  |  |  |
Organization, Consolidation and Presentation of Financial Statements Disclosure [Line Items] |  |  |  |  |
Senior notes, effective interest rate | 8.75% |  | 8.75% |  |
Principal amount of outstanding borrowings | $ 2,500,000 |  |  |  |
Deerfield | Minimum |  |  |  |  |
Organization, Consolidation and Presentation of Financial Statements Disclosure [Line Items] |  |  |  |  |
Available amount of credit facility under covenant restrictions for each quarter end after current fiscal |  | $ 25,000,000 |  |  |
Deerfield | 2019 notes |  |  |  |  |
Organization, Consolidation and Presentation of Financial Statements Disclosure [Line Items] |  |  |  |  |
Senior notes, effective interest rate | 9.75% |  | 9.75% |  |
Principal amount of outstanding borrowings |  |  |  |  | $ 160,000,000
Deerfield | Tranche B notes |  |  |  |  |
Organization, Consolidation and Presentation of Financial Statements Disclosure [Line Items] |  |  |  |  |
Senior notes, effective interest rate | 8.75% |  | 8.75% |  |

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