Description of Business and Significant Accounting Policies (Tables)

3 Months Ended

Mar. 31, 2019

Schedule of Potentially Dilutive Common Stock Equivalent Securities

The computation of basic and diluted net loss per share for the three months ended March 31, 2019 and 2018 excludes the common stock equivalents of the following potentially dilutive securities because their inclusion, as the Company is in a net loss position, would be anti-dilutive:

	Three months ended March 31,
	2019		2018
Vesting of restricted stock units		1,314,218		1,073,036
Conversion of convertible notes into common stock		3,629,627		14,154,500
Conversion of convertible related party notes into common stock		21,909,541		18,743,500
Exercise of common stock warrants		31,851		31,856
Employee stock purchase plan		141,568		111,020
Exercise of common stock options		10,846,738		7,212,239
Exercise of warrants associated with public offering		26,666,667		—
Exercise of warrants associated with direct placement		14,000,000		—
		78,540,210		41,326,151