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Schedule of Potentially Dilutive Common Stock Equivalent Securities (Detail) - shares
3 Months Ended
Mar. 31, 2019
Mar. 31, 2018
Antidilutive Securities Excluded From Computation Of Earnings Per Share [Line Items]    
Anti-dilutive securities excluded from computation of earnings per share 78,540,210 41,326,151
Vesting of Restricted Stock Units    
Antidilutive Securities Excluded From Computation Of Earnings Per Share [Line Items]    
Anti-dilutive securities excluded from computation of earnings per share 1,314,218 1,073,036
Conversion of Convertible Notes into Common Stock    
Antidilutive Securities Excluded From Computation Of Earnings Per Share [Line Items]    
Anti-dilutive securities excluded from computation of earnings per share 3,629,627 14,154,500
Conversion of Convertible Related Party Notes into Common Stock    
Antidilutive Securities Excluded From Computation Of Earnings Per Share [Line Items]    
Anti-dilutive securities excluded from computation of earnings per share 21,909,541 18,743,500
Exercise of Common Stock Warrants    
Antidilutive Securities Excluded From Computation Of Earnings Per Share [Line Items]    
Anti-dilutive securities excluded from computation of earnings per share 31,851 31,856
Employee Stock Purchase Plan    
Antidilutive Securities Excluded From Computation Of Earnings Per Share [Line Items]    
Anti-dilutive securities excluded from computation of earnings per share 141,568 111,020
Exercise of Common Stock Options    
Antidilutive Securities Excluded From Computation Of Earnings Per Share [Line Items]    
Anti-dilutive securities excluded from computation of earnings per share 10,846,738 7,212,239
Exercise of Warrants Associated with Public Offering    
Antidilutive Securities Excluded From Computation Of Earnings Per Share [Line Items]    
Anti-dilutive securities excluded from computation of earnings per share 26,666,667  
Exercise of Warrants Associated with Direct Placement    
Antidilutive Securities Excluded From Computation Of Earnings Per Share [Line Items]    
Anti-dilutive securities excluded from computation of earnings per share 14,000,000