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Condensed Consolidated Statements of Operations - USD ($)
shares in Thousands, $ in Thousands
 3 Months Ended
Mar. 31, 2019
Mar. 31, 2018
Revenues:    
Total revenues $ 17,448 $ 3,465
Expenses:    
Cost of goods sold 4,020 4,008
Research and development 1,667 2,644
Selling, general and administrative 25,673 20,618
(Gain) loss on foreign currency translation (1,935) 2,984
Total expenses 30,962 30,254
Loss from operations (13,514) (26,789)
Other (expense) income:    
Interest income 318 106
Interest expense on notes (593) (1,794)
Interest expense on note payable to related party (1,080) (1,114)
Loss on extinguishment of debt   (825)
Other income (expense) (14) 31
Total other expense (1,369) (3,596)
Loss before provision for income taxes (14,883) (30,385)
Net loss $ (14,883) $ (30,385)
Net loss per share - basic and diluted $ (0.08) $ (0.25)
Shares used to compute basic and diluted net loss per share 187,434 120,911
Commercial product sales    
Revenues:    
Total revenues $ 5,076 $ 3,402
Collaborations and services    
Revenues:    
Total revenues 12,372 $ 63
Expenses:    
Cost of revenue $ 1,537