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Fair Value of Financial Instruments (Detail) - USD ($)
Mar. 31, 2019
Dec. 31, 2018
Financial liabilities:    
Financial liabilities fair value $ 118,800 $ 102,000
Carrying Value    
Financial liabilities:    
Financial liabilities fair value 111,400 111,400
Estimate of Fair Value Measurement | Fair Value, Inputs, Level 3    
Financial liabilities:    
Financial liabilities fair value 118,800 102,000
2021 Notes    
Financial liabilities:    
Financial liabilities fair value 19,600 17,500
2021 Notes | Carrying Value    
Financial liabilities:    
Financial liabilities fair value 19,100 19,100
2021 Notes | Estimate of Fair Value Measurement | Fair Value, Inputs, Level 3    
Financial liabilities:    
Financial liabilities fair value 19,600 17,500
Facility Financing Obligation    
Financial liabilities:    
Financial liabilities fair value 11,400 11,400
Facility Financing Obligation | Carrying Value    
Financial liabilities:    
Financial liabilities fair value 11,400 11,300
Facility Financing Obligation | Estimate of Fair Value Measurement | Fair Value, Inputs, Level 3    
Financial liabilities:    
Financial liabilities fair value 11,400 11,400
Note Payable to Related Party    
Financial liabilities:    
Financial liabilities fair value 69,400 55,000
Note Payable to Related Party | Carrying Value    
Financial liabilities:    
Financial liabilities fair value 72,000 72,100
Note Payable to Related Party | Estimate of Fair Value Measurement | Fair Value, Inputs, Level 3    
Financial liabilities:    
Financial liabilities fair value 69,400 55,000
Milestone Rights Liability    
Financial liabilities:    
Financial liabilities fair value 18,400 18,100
Milestone Rights Liability | Carrying Value    
Financial liabilities:    
Financial liabilities fair value 8,900 8,900
Milestone Rights Liability | Estimate of Fair Value Measurement | Fair Value, Inputs, Level 3    
Financial liabilities:    
Financial liabilities fair value $ 18,400 $ 18,100