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Commitments and Contingencies - Additional Information (Detail)
$ / shares in Units, € in Millions
 3 Months Ended
Dec. 19, 2018
USD ($)
$ / shares
shares
Apr. 05, 2018
USD ($)
$ / shares
shares
Nov. 29, 2017
USD ($)
Oct. 23, 2017
shares
May 05, 2017
USD ($)
Mar. 31, 2019
USD ($)
Mar. 31, 2019
EUR (€)
Jun. 30, 2018
USD ($)
Vehicle
Mar. 31, 2018
USD ($)
Mar. 31, 2019
EUR (€)
Jan. 01, 2019
USD ($)
Jul. 01, 2013
USD ($)
Commitments And Contingencies [Line Items]                        
Purchase commitment amount under insulin supply agreement | €             € 90.3          
Long term purchase commitment remaining amount | €                   € 84.1    
Supply Agreement expiration period           Dec. 31, 2024 Dec. 31, 2024          
Supply Agreement renewal period           2 years 2 years          
Operating lease, non-current liabilities           $ 3,615,000            
Operating lease costs           500,000            
Operating lease, cash paid           500,000            
Variable lease costs           $ 100,000            
Operating lease, weighted average discount rate           7.20%       7.20%    
Operating lease, weighted-average remaining lease term           3 years 9 months 18 days       3 years 9 months 18 days    
Vehicle Leases | Lease Agreement with Enterprise                        
Commitments And Contingencies [Line Items]                        
Number of vehicle leases | Vehicle               118        
Operating lease rent expenses               $ 83,000        
Lease expiration date               48 months        
Operating lease right-of-use assets                     $ 1,600,000  
Operating lease liabilities           $ 1,300,000         1,600,000  
Operating lease, current assets           1,600,000            
Operating lease, other current liabilities           600,000            
Common Stock                        
Commitments And Contingencies [Line Items]                        
Number of shares sold in underwritten public offering | shares       973,236                
Purchase Agreements                        
Commitments And Contingencies [Line Items]                        
Stock purchase agreements date   Apr. 05, 2018                    
Warrant expiration date   Apr. 09, 2019                    
Purchase Agreements | Common Stock                        
Commitments And Contingencies [Line Items]                        
Number of shares sold in underwritten public offering | shares   14,000,000                    
Amount of net proceeds from issuance of securities   $ 26,400,000                    
Exchange price per share | $ / shares   $ 2.00                    
Purchase Agreements | Warrants                        
Commitments And Contingencies [Line Items]                        
Warrants to purchase of common stock | shares   14,000,000                    
Exercise price of warrants | $ / shares   $ 2.38                    
Deerfield | Milestone Rights Liability | Maximum                        
Commitments And Contingencies [Line Items]                        
Contingent liability for milestone payments           $ 90,000,000           $ 90,000,000
Leerink Partners LLC | Underwriting Agreement                        
Commitments And Contingencies [Line Items]                        
Stock purchase agreements date Dec. 26, 2018                      
Warrant expiration date Dec. 26, 2019                      
Leerink Partners LLC | Underwriting Agreement | Common Stock                        
Commitments And Contingencies [Line Items]                        
Number of shares sold in underwritten public offering | shares 26,666,667                      
Amount of net proceeds from issuance of securities $ 37,300,000                      
Exchange price per share | $ / shares $ 1.50                      
Leerink Partners LLC | Underwriting Agreement | Warrants                        
Commitments And Contingencies [Line Items]                        
Warrants to purchase of common stock | shares 26,666,667                      
Exercise price of warrants | $ / shares $ 1.60                      
Russell Ranch Road II LLC | Office Lease                        
Commitments And Contingencies [Line Items]                        
Operating lease rent expenses     $ 35,969   $ 40,951              
Operating lease right-of-use assets                     3,200,000  
Operating lease liabilities                     3,500,000  
Percentage of annual increase in lease payment     3.00%   3.00%              
Lease expiration date     Jan. 31, 2023   Jan. 31, 2023              
Lease renewal option     5 years   5 years              
Maximum reimbursable amount for tenant improvements     $ 56,325                  
Maintenance fee of common area     $ 0                  
Operating lease, current liabilities                     900,000  
Operating lease rent expenses                 $ 100,000      
Operating lease, non-current liabilities                     $ 2,600,000