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Consolidated Statements of Cash Flows - USD ($)
 3 Months Ended
Mar. 31, 2019
Mar. 31, 2018
CASH FLOWS FROM OPERATING ACTIVITIES:    
Net loss $ (14,883,000) $ (30,385,000)
Adjustments to reconcile net loss to net cash (used in) provided by operating activities:    
Depreciation, amortization and accretion 367,000 706,000
Amortization of right-of-use assets 395,000  
Stock-based compensation expense 999,000 1,943,000
Restricted stock unit award 105,000  
Loss on extinguishment of debt   825,000
(Gain) Loss on foreign currency translation (1,935,000) 2,984,000
Interest on note payable to related party 1,134,000 1,122,000
Write-off of inventory 0 602,000
Other, net (1,000) 110,000
Changes in operating assets and liabilities:    
Accounts receivable, net 258,000 1,128,000
Inventory (123,000) (1,836,000)
Prepaid expenses and other current assets 164,000 656,000
Right-of-use and other assets (340,000) 38,000
Accounts payable 1,599,000 (2,008,000)
Accrued expenses and other current liabilities 2,336,000 2,675,000
Deferred revenue 686,000 (63,000)
Recognized loss on purchase commitments (1,963,000) (147,000)
Operating lease payments (395,000)  
Net cash used in operating activities (11,597,000) (21,650,000)
CASH FLOWS FROM INVESTING ACTIVITIES:    
Purchase of property and equipment (269,000)  
Purchase of short-term investments (24,764,000)  
Net cash used in investing activities (25,033,000)  
CASH FLOWS FROM FINANCING ACTIVITIES:    
Payment of employment taxes related to vested restricted stock units   (81,000)
Other 3,000  
Net cash provided by financing activities 3,000 528,000
NET DECREASE IN CASH AND CASH EQUIVALENTS AND RESTRICTED CASH (36,627,000) (21,122,000)
CASH AND CASH EQUIVALENTS AND RESTRICTED CASH, BEGINNING OF PERIOD 71,684,000 48,355,000
CASH AND CASH EQUIVALENTS AND RESTRICTED CASH, END OF PERIOD 35,057,000 27,233,000
SUPPLEMENTAL CASH FLOWS DISCLOSURES:    
Interest paid in cash, net of amounts capitalized   1,860,000
NON-CASH INVESTING AND FINANCING ACTIVITIES:    
Payment of note obligations through common stock issuance   9,407,000
Payment of note payable to related party through common stock issuance   8,160,000
Accrued but unpaid debt issuance costs related to note payable to related party   75,000
Payment of interest on senior convertible notes through common stock issuance 534,000  
Property and equipment in progress in accounts payable 246,000  
Common stock issuance to settle employee stock purchase plan liability 317,000  
Addition of right-of-use assets $ 5,192,000  
At-the-market Issuance    
CASH FLOWS FROM FINANCING ACTIVITIES:    
Proceeds from issuance of common stock   634,000
Issuance costs   $ (25,000)