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Collaborations and Licensing Arrangements - Additional Information (Detail 1) - USD ($) $ in Millions | May 31, 2018 | Dec. 31, 2016
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Collaboration and License Agreement | Receptor | Revenue, Remaining Performance Obligation, Expected Timing of Satisfaction, Start Date: 2017-01-01 |  |
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] |  |
Deferred revenue - nonrefundable license fee |  | $ 1.0
Deferred revenue recognition period |  | 4 years
License and Distribution Agreement | Cipla Ltd | Revenue, Remaining Performance Obligation, Expected Timing of Satisfaction, Start Date: 2018-06-01 |  |
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] |  |
Deferred revenue - nonrefundable license fee | $ 2.2 |
Deferred revenue recognition period | 15 years |

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