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Fair Value of Financial Instruments (Detail) - USD ($)
Jun. 30, 2019
Dec. 31, 2018
Financial liabilities:    
Financial liabilities fair value $ 105,000 $ 102,000
Facility Financing Obligation    
Financial liabilities:    
Financial liabilities fair value 9,000 11,400
Senior Convertible Notes    
Financial liabilities:    
Financial liabilities fair value 18,000 17,500
Related Party Notes    
Financial liabilities:    
Financial liabilities fair value 59,500 55,000
Milestone Rights Liability    
Financial liabilities:    
Financial liabilities fair value 18,500 18,100
Carrying Value    
Financial liabilities:    
Financial liabilities fair value 108,900 111,400
Carrying Value | Facility Financing Obligation    
Financial liabilities:    
Financial liabilities fair value 9,000 11,300
Carrying Value | Senior Convertible Notes    
Financial liabilities:    
Financial liabilities fair value 19,000 19,100
Carrying Value | Related Party Notes    
Financial liabilities:    
Financial liabilities fair value 72,000 72,100
Carrying Value | Milestone Rights Liability    
Financial liabilities:    
Financial liabilities fair value 8,900 8,900
Estimate of Fair Value Measurement | Fair Value, Inputs, Level 3    
Financial liabilities:    
Financial liabilities fair value 105,000 102,000
Estimate of Fair Value Measurement | Facility Financing Obligation | Fair Value, Inputs, Level 3    
Financial liabilities:    
Financial liabilities fair value 9,000 11,400
Estimate of Fair Value Measurement | Senior Convertible Notes | Fair Value, Inputs, Level 3    
Financial liabilities:    
Financial liabilities fair value 18,000 17,500
Estimate of Fair Value Measurement | Related Party Notes | Fair Value, Inputs, Level 3    
Financial liabilities:    
Financial liabilities fair value 59,500 55,000
Estimate of Fair Value Measurement | Milestone Rights Liability | Fair Value, Inputs, Level 3    
Financial liabilities:    
Financial liabilities fair value $ 18,500 $ 18,100