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Borrowings - Facility Financing Obligation - Additional Information (Detail) - USD ($)
 3 Months Ended 9 Months Ended 12 Months Ended
Sep. 30, 2019
Sep. 30, 2019
Dec. 31, 2018
Jun. 30, 2019
Jul. 01, 2013
Debt Instrument [Line Items]          
Milestone rights liability $ 7,263,000 $ 7,263,000 $ 7,201,000    
Deerfield | Facility Financing Obligation          
Debt Instrument [Line Items]          
Remaining milestone rights liability 8,900,000 8,900,000 8,900,000    
Required payment for milestone liability 5,000,000        
Milestone interest expense   3,400,000 3,400,000    
Milestone rights liability 7,300,000 7,300,000 7,300,000    
Deerfield | Facility Financing Obligation | Accrued Expenses and Other Current Liabilities          
Debt Instrument [Line Items]          
Milestone rights liability, current $ 1,600,000 $ 1,600,000 $ 1,600,000    
Milestone Rights Liability | Deerfield          
Debt Instrument [Line Items]          
Contingent liability for milestone payments       $ 75,000,000  
Contingent liability for milestone payments, remain payable amount         $ 75,000,000
Milestone Rights Liability | Deerfield | Maximum          
Debt Instrument [Line Items]          
Contingent liability for milestone payments       $ 90,000,000 $ 90,000,000