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Schedule of Revenue from Collaborations and Services (Detail) - USD ($) $ in Thousands | 3 Months Ended | 12 Months Ended
--- | --- | ---
Dec. 31, 2019 | Sep. 30, 2019 | Jun. 30, 2019 | Mar. 31, 2019 | Dec. 31, 2018 | Sep. 30, 2018 | Jun. 30, 2018 | Mar. 31, 2018 | Dec. 31, 2019 | Dec. 31, 2018
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |  |  |  |
Total revenue from collaborations and services | $ 15,993 | $ 14,595 | $ 15,002 | $ 17,448 | $ 16,031 | $ 4,469 | $ 3,893 | $ 3,465 | $ 63,038 | $ 27,859
Collaborations and services |  |  |  |  |  |  |  |  |  |
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |  |  |  |
Total revenue from collaborations and services |  |  |  |  |  |  |  |  | 37,734 | 10,583
Collaborations and services | License Agreement | United Therapeutics Corporation |  |  |  |  |  |  |  |  |  |
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |  |  |  |
Total revenue from collaborations and services |  |  |  |  |  |  |  |  | 31,229 | 6,386
Collaborations and services | Research Agreement | United Therapeutics Corporation |  |  |  |  |  |  |  |  |  |
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |  |  |  |
Total revenue from collaborations and services |  |  |  |  |  |  |  |  | 6,032 | 3,758
Collaborations and services | Collaboration and License Agreement | Receptor |  |  |  |  |  |  |  |  |  |
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |  |  |  |
Total revenue from collaborations and services |  |  |  |  |  |  |  |  | 250 | 341
Collaborations and services | Distribution Agreement | Cipla Ltd |  |  |  |  |  |  |  |  |  |
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |  |  |  |
Total revenue from collaborations and services |  |  |  |  |  |  |  |  | 148 | $ 98
Collaborations and services | Distribution Agreement | Biomm S.A. |  |  |  |  |  |  |  |  |  |
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |  |  |  |
Total revenue from collaborations and services |  |  |  |  |  |  |  |  | $ 75 |

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