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Income Taxes - Additional Information (Detail) - USD ($) |  | 1 Months Ended | 12 Months Ended
--- | --- | --- | ---
Mar. 27, 2020 | Aug. 31, 2004 | Dec. 31, 2020 | Dec. 31, 2019
Income Taxes [Line Items] |  |  |  |
Income tax benefit |  |  | $ 218,000 |
Valuation allowance of deferred tax asset |  |  | 675,463,000 | $ 670,617,000
Change in the valuation allowance |  |  | 4,846,000 | 5,252,000
Federal operating loss carryforwards |  |  | 2,400,000,000 |
State operating loss carryforwards |  |  | 1,300,000,000 |
Federal operation loss carryforwards, not subject to expiration |  |  | $ 395,200,000 |
Operating loss carryforwards, limitations on use |  |  | Pursuant to Internal Revenue Code (“IRC”) Sections 382 and 383, annual use of the Company’s federal and state net operating loss and research and development credit carryforwards may be limited in the event a cumulative change in ownership of more than 50% occurs within a three-year period. |
Net operating loss carryforwards |  | $ 216,000,000.0 |  |
Net operating loss and credit carryforwards, annual use limitation |  | $ 13,000,000.0 |  |
Research and development credits |  |  | $ 79,455,000 | 80,488,000
Research and development credits begin to expire |  |  | 2020 |
Research and development credits expire |  |  | $ 1,000,000.0 |
Undistributed earnings from its foreign subsidiaries |  |  | 0 |
Adjustment of deferred tax liability due to adoption of new leases guidance |  |  | 742,000 | 958,000
Adjustment of deferred tax asset due to adoption of new leases guidance |  |  | 676,205,000 | 671,575,000
Tax provisions and other stimulus measures | $ 2,000,000,000,000 |  |  |
Topic 842 |  |  |  |
Income Taxes [Line Items] |  |  |  |
Adjustment of deferred tax liability due to adoption of new leases guidance |  |  |  | 700,000
Adjustment of deferred tax asset due to adoption of new leases guidance |  |  |  | $ 700,000
Federal |  |  |  |
Income Taxes [Line Items] |  |  |  |
Research and development credits |  |  | $ 54,200,000 |
Research and development credits begin to expire |  |  | 2024 |
State |  |  |  |
Income Taxes [Line Items] |  |  |  |
Research and development credits |  |  | $ 25,300,000 |
New Jersey |  |  |  |
Income Taxes [Line Items] |  |  |  |
Research and development credits begin to expire |  |  | 2020 |
Connecticut |  |  |  |
Income Taxes [Line Items] |  |  |  |
Research and development credits |  |  | $ 100,000 |
Research and development credits not expire |  |  | $ 15,700,000 |

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