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Commitments and Contingencies - Additional Information (Detail) |  |  | 1 Months Ended | 3 Months Ended | 12 Months Ended |  |  |  |
--- | --- | --- | --- | --- | --- | --- | --- | --- | ---
Dec. 26, 2019 $ / shares shares | Dec. 23, 2019 $ / shares | Aug. 31, 2019 | Dec. 31, 2018 $ / shares shares | Nov. 30, 2017 USD ($) | May 31, 2017 USD ($) | Jun. 30, 2018 USD ($) Vehicle | Dec. 31, 2020 USD ($) $ / shares shares | Dec. 31, 2019 USD ($) Vehicle | Nov. 30, 2020 $ / shares shares | Aug. 06, 2019 $ / shares shares | Jan. 01, 2019 USD ($) | Jul. 01, 2013 USD ($)
Commitments And Contingencies [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |
Purchase obligation extended term |  |  | 2026 |  |  |  |  |  |  |  |  |  |
Supply Agreement expiration period |  |  |  |  |  |  |  | Dec. 31, 2026 |  |  |  |  |
Supply Agreement renewal period |  |  |  |  |  |  |  | 2 years |  |  |  |  |
Foreign currency hedging transactions period |  |  |  |  |  |  |  | 90 days |  |  |  |  |
Operating lease, non-current liabilities |  |  |  |  |  |  |  | $ 1,202,000 | $ 2,514,000 |  |  |  |
Operating lease costs |  |  |  |  |  |  |  | 1,400,000 | 1,500,000 |  |  |  |
Operating lease, cash paid |  |  |  |  |  |  |  | 1,800,000 | 1,800,000 |  |  |  |
Variable lease costs |  |  |  |  |  |  |  | $ 400,000 | $ 400,000 |  |  |  |
Operating lease, weighted average discount rate |  |  |  |  |  |  |  | 7.50% | 7.50% |  |  |  |
Operating lease, weighted-average remaining lease term |  |  |  |  |  |  |  | 1 year 10 months 24 days | 3 years |  |  |  |
Underwriting Agreement with Leerink Partners LLC |  |  |  |  |  |  |  |  |  |  |  |  |
Commitments And Contingencies [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |
Exercise price of warrants | $ / shares |  | $ 1.311 |  |  |  |  |  |  |  |  |  |  |
Stock purchase agreements date |  |  |  | Dec. 31, 2018 |  |  |  |  |  |  |  |  |
Warrants expiration, date |  | Jun. 26, 2020 |  | Dec. 26, 2019 |  |  |  |  |  |  |  |  |
Warrants expired unexercised | shares | 11,583,333 |  |  |  |  |  |  |  |  |  |  |  |
Remaining warrants available for purchase | shares | 7,250,000 |  |  |  |  |  |  | 7,250,000 |  |  |  |  |
Underwriting Agreement with Leerink Partners LLC | Common Stock |  |  |  |  |  |  |  |  |  |  |  |  |
Commitments And Contingencies [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |
Exchange price per share | $ / shares |  |  |  | $ 1.50 |  |  |  |  |  |  |  |  |
Underwriting Agreement with Leerink Partners LLC | Warrant |  |  |  |  |  |  |  |  |  |  |  |  |
Commitments And Contingencies [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |
Exercise price of warrants | $ / shares | $ 1.60 |  |  | $ 1.60 |  |  |  | $ 1.60 |  |  |  |  |
Underwriting Agreement with Leerink Partners LLC | Initial Public Offering | Common Stock |  |  |  |  |  |  |  |  |  |  |  |  |
Commitments And Contingencies [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |
Number of shares sold during the period | shares |  |  |  | 26,666,667 |  |  |  |  |  |  |  |  |
Lease Agreement with Enterprise | Vehicle Leases |  |  |  |  |  |  |  |  |  |  |  |  |
Commitments And Contingencies [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |
Number of vehicle leases | Vehicle |  |  |  |  |  |  | 119 |  | 90 |  |  |  |
Operating lease rent expenses |  |  |  |  |  |  | $ 83,000 |  | $ 70,000 |  |  |  |
Number of vehicle leases removed | Vehicle |  |  |  |  |  |  |  |  | 29 |  |  |  |
Gain or loss recorded for leases removed |  |  |  |  |  |  |  |  | $ 0 |  |  |  |
Lease expiration period |  |  |  |  |  |  | 48 months |  |  |  |  |  |
Operating lease right-of-use assets |  |  |  |  |  |  |  |  |  |  |  | $ 1,600,000 |
Operating lease liabilities |  |  |  |  |  |  |  |  |  |  |  | 1,900,000 |
Operating lease, non-current other assets |  |  |  |  |  |  |  |  |  |  |  | 1,600,000 |
Operating lease, other current liabilities |  |  |  |  |  |  |  |  |  |  |  | 600,000 |
Operating lease, non-current liabilities |  |  |  |  |  |  |  |  |  |  |  | 1,300,000 |
Cost of Goods Sold |  |  |  |  |  |  |  |  |  |  |  |  |
Commitments And Contingencies [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |
Payment of long term purchase commitment, amendment fees |  |  |  |  |  |  |  | $ 0 | $ 2,800,000 |  |  |  |
Maximum | Underwriting Agreement with Leerink Partners LLC | Warrant |  |  |  |  |  |  |  |  |  |  |  |  |
Commitments And Contingencies [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |
Warrants to purchase of common stock | shares |  |  |  | 26,666,667 |  |  |  |  |  |  |  |  |
MidCap Credit Facility |  |  |  |  |  |  |  |  |  |  |  |  |
Commitments And Contingencies [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |
Exercise price of warrants | $ / shares |  |  |  |  |  |  |  |  |  | $ 2.91 | $ 1.11 |  |
Warrants to purchase of common stock | shares |  |  |  |  |  |  |  |  |  | 111,853 | 1,171,614 |  |
Deerfield | Milestone Rights Liability |  |  |  |  |  |  |  |  |  |  |  |  |
Commitments And Contingencies [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |
Contingent liability remain payable |  |  |  |  |  |  |  | 70,000,000.0 |  |  |  |  |
Accrued expenses and other current liabilities |  |  |  |  |  |  |  | 1,300,000 |  |  |  |  |
Milestone rights and other liabilities |  |  |  |  |  |  |  | $ 5,900,000 |  |  |  |  |
Deerfield | Milestone Rights Liability | Maximum |  |  |  |  |  |  |  |  |  |  |  |  |
Commitments And Contingencies [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |
Contingent liability for milestone payments |  |  |  |  |  |  |  |  |  |  |  |  | $ 90,000,000.0
Russell Ranch Road II LLC | Office Lease |  |  |  |  |  |  |  |  |  |  |  |  |
Commitments And Contingencies [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |
Operating lease rent expenses |  |  |  |  | $ 35,969 | $ 40,951 |  |  |  |  |  |  |
Operating lease right-of-use assets |  |  |  |  |  |  |  |  |  |  |  | 3,200,000 |
Operating lease liabilities |  |  |  |  |  |  |  |  |  |  |  | 3,500,000 |
Operating lease, other current liabilities |  |  |  |  |  |  |  |  |  |  |  | 900,000 |
Operating lease, non-current liabilities |  |  |  |  |  |  |  |  |  |  |  | $ 2,600,000 |
Percentage of annual increase in lease payment |  |  |  |  | 3.00% | 3.00% |  |  |  |  |  |  |
Lease expiration date |  |  |  |  | Jan. 31, 2023 | Jan. 31, 2023 |  |  |  |  |  |  |
Lease renewal option |  |  |  |  | 5 years | 5 years |  |  |  |  |  |  |
Reimbursement amount received for tenant improvements |  |  |  |  | $ 56,325 |  |  |  |  |  |  |  |

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