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Consolidated Statements of Operations - USD ($)
shares in Thousands
 12 Months Ended
Dec. 31, 2020
Dec. 31, 2019
Revenues:    
Total revenues $ 65,144,000 $ 63,038,000
Expenses:    
Cost of goods sold 15,084,000 20,078,000
In-process research and development 13,233,000  
Research and development 6,248,000 6,900,000
Selling, general and administrative 59,040,000 74,669,000
Impairment of commitment asset 1,889,000 0
Loss (gain) on foreign currency translation 8,006,000 (1,913,000)
Total expenses 113,057,000 107,635,000
Loss from operations (47,913,000) (44,597,000)
Other (expense) income:    
Interest income 167,000 997,000
Interest expense on notes (4,316,000) (6,304,000)
Interest expense on promissory notes (5,155,000) (4,602,000)
(Loss) gain on extinguishment of debt (264,000) 3,529,000
Other expense 23,000 (926,000)
Total other expense (9,545,000) (7,306,000)
Loss before income tax expense (57,458,000) (51,903,000)
Benefit from income taxes 218,000  
Net loss $ (57,240,000) $ (51,903,000)
Net loss per share — basic and diluted $ (0.26) $ (0.27)
Shares used to compute net loss per share — basic and diluted 222,585 195,584
Commercial product sales    
Revenues:    
Total revenues $ 32,324,000 $ 25,304,000
Collaborations and services    
Revenues:    
Total revenues 32,820,000 37,734,000
Expenses:    
Cost of revenue $ 9,557,000 $ 7,901,000