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Amount before allocation of valuation allowances of deferred tax asset attributable to deductible domestic operating loss carryforwards. Excludes state and local operating loss carryforwards.

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Income Taxes - Additional Information (Detail) - USD ($)		1 Months Ended	12 Months Ended
	Mar. 27, 2020	Aug. 31, 2004	Dec. 31, 2020	Dec. 31, 2019
Income Taxes [Line Items]
Income tax benefit			$ 218,000
Valuation allowance of deferred tax asset			675,463,000	$ 670,617,000
Change in the valuation allowance			4,846,000	5,252,000
Federal operating loss carryforwards			2,400,000,000
State operating loss carryforwards			1,300,000,000
Federal operation loss carryforwards, not subject to expiration			$ 395,200,000
Operating loss carryforwards, limitations on use			Pursuant to Internal Revenue Code (“IRC”) Sections 382 and 383, annual use of the Company’s federal and state net operating loss and research and development credit carryforwards may be limited in the event a cumulative change in ownership of more than 50% occurs within a three-year period.
Net operating loss carryforwards		$ 216,000,000.0
Net operating loss and credit carryforwards, annual use limitation		$ 13,000,000.0
Research and development credits			$ 79,455,000	80,488,000
Research and development credits begin to expire			2020
Research and development credits expire			$ 1,000,000.0
Undistributed earnings from its foreign subsidiaries			0
Adjustment of deferred tax liability due to adoption of new leases guidance			742,000	958,000
Adjustment of deferred tax asset due to adoption of new leases guidance			676,205,000	671,575,000
Tax provisions and other stimulus measures	$ 2,000,000,000,000
Topic 842
Income Taxes [Line Items]
Adjustment of deferred tax liability due to adoption of new leases guidance				700,000
Adjustment of deferred tax asset due to adoption of new leases guidance				$ 700,000
Federal
Income Taxes [Line Items]
Research and development credits			$ 54,200,000
Research and development credits begin to expire			2024
State
Income Taxes [Line Items]
Research and development credits			$ 25,300,000
New Jersey
Income Taxes [Line Items]
Research and development credits begin to expire			2020
Connecticut
Income Taxes [Line Items]
Research and development credits			$ 100,000
Research and development credits not expire			$ 15,700,000