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Description of Business and Significant Accounting Policies - Additional Information (Detail) |  |  | 1 Months Ended | 3 Months Ended |  |  |  |  |
--- | --- | --- | --- | --- | --- | --- | --- | --- | ---
Apr. 22, 2021 USD ($) | Apr. 10, 2020 USD ($) | Mar. 31, 2021 USD ($) | Mar. 31, 2021 USD ($) Segment Contract | Mar. 31, 2020 USD ($) | Dec. 31, 2020 USD ($) | Sep. 30, 2020 USD ($) | Dec. 31, 2019 USD ($) | Aug. 31, 2019 USD ($) | Jul. 01, 2013 USD ($)
Organization Consolidation And Presentation Of Financial Statements Disclosure [Line Items] |  |  |  |  |  |  |  |  |  |
Accumulated deficit |  |  | $ (3,062,059,000) | $ (3,062,059,000) |  | $ (3,049,143,000) |  |  |  |
Principal amount |  |  | 338,400,000 | 338,400,000 |  |  |  |  |  |
Cash and cash equivalents |  |  | 247,833,000 | 247,833,000 |  | 67,005,000 |  |  |  |
Short-term investments |  |  | 28,962,000 | 28,962,000 |  |  |  |  |  |
Long-term investments |  |  | 1,480,000 | $ 1,480,000 |  |  |  |  |  |
Debt issuance amount |  |  | $ 230,000,000.0 |  |  |  |  |  |  |
Debt issuance percentage |  |  | 2.50% |  |  |  |  |  |  |
Number of operating segment | Segment |  |  |  | 1 |  |  |  |  |  |
Accretion or amortization |  |  |  | $ 0 |  |  |  |  |  |
Allowance for credit losses on held-to-maturity securities |  |  | $ 0 | $ 0 |  |  |  |  |  |
ASU 2020-06 |  |  |  |  |  |  |  |  |  |
Organization Consolidation And Presentation Of Financial Statements Disclosure [Line Items] |  |  |  |  |  |  |  |  |  |
Change in accounting principle accounting standards update adopted |  |  | true | true |  |  |  |  |  |
Change in accounting principle accounting standards update adoption date |  |  | Jan. 01, 2021 | Jan. 01, 2021 |  |  |  |  |  |
Change in accounting principle accounting standards update immaterial effect |  |  | true | true |  |  |  |  |  |
Change in accounting principle accounting standards update early adoption |  |  | true | true |  |  |  |  |  |
Commitment Asset | Other Expense |  |  |  |  |  |  |  |  |  |
Organization Consolidation And Presentation Of Financial Statements Disclosure [Line Items] |  |  |  |  |  |  |  |  |  |
Asset impairment |  |  |  |  | $ 1,500,000 |  |  |  |  |
Paycheck Protection Program Loan, CARES Act |  |  |  |  |  |  |  |  |  |
Organization Consolidation And Presentation Of Financial Statements Disclosure [Line Items] |  |  |  |  |  |  |  |  |  |
Principal amount |  |  | $ 4,900,000 | $ 4,900,000 |  | 4,900,000 |  |  |  |
Proceeds from loans |  | $ 4,900,000 |  |  |  |  |  |  |  |
Insulin |  |  |  |  |  |  |  |  |  |
Organization Consolidation And Presentation Of Financial Statements Disclosure [Line Items] |  |  |  |  |  |  |  |  |  |
Loss on purchase commitments |  |  | 89,100,000 | $ 89,100,000 |  | 95,300,000 |  |  |  |
Loss on purchase commitments, number of new contracts recognized | Contract |  |  |  | 0 |  |  |  |  |  |
Maximum | AFREZZA product sales |  |  |  |  |  |  |  |  |  |
Organization Consolidation And Presentation Of Financial Statements Disclosure [Line Items] |  |  |  |  |  |  |  |  |  |
Sales return right following product expiration in months |  |  |  | 12 months |  |  |  |  |  |
Minimum | AFREZZA product sales |  |  |  |  |  |  |  |  |  |
Organization Consolidation And Presentation Of Financial Statements Disclosure [Line Items] |  |  |  |  |  |  |  |  |  |
Sales return right following product expiration in months |  |  |  | 6 months |  |  |  |  |  |
MidCap Credit Facility |  |  |  |  |  |  |  |  |  |
Organization Consolidation And Presentation Of Financial Statements Disclosure [Line Items] |  |  |  |  |  |  |  |  |  |
Principal amount |  |  | 50,000,000.0 | $ 50,000,000.0 |  | $ 50,000,000.0 |  |  |  |
Principal amount |  |  |  |  |  |  |  |  | $ 110,000,000.0 |
Amount outstanding |  |  |  |  |  |  | $ 50,000,000.0 | $ 50,000,000.0 |  |
Commitment asset |  |  |  |  |  |  |  |  | $ 1,500,000 |
MidCap Credit Facility | Subsequent Event |  |  |  |  |  |  |  |  |  |
Organization Consolidation And Presentation Of Financial Statements Disclosure [Line Items] |  |  |  |  |  |  |  |  |  |
Principal prepayment against outstanding term loans | $ 10,000,000.0 |  |  |  |  |  |  |  |  |
Milestone Rights Liability | Deerfield |  |  |  |  |  |  |  |  |  |
Organization Consolidation And Presentation Of Financial Statements Disclosure [Line Items] |  |  |  |  |  |  |  |  |  |
Contingent liability remain payable |  |  | $ 70,000,000.0 | $ 70,000,000.0 |  |  |  |  |  |
Milestone Rights Liability | Maximum | Deerfield |  |  |  |  |  |  |  |  |  |
Organization Consolidation And Presentation Of Financial Statements Disclosure [Line Items] |  |  |  |  |  |  |  |  |  |
Contingent liability for milestone payments |  |  |  |  |  |  |  |  |  | $ 90,000,000.0

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- Definition The aggregate amount of write-downs for impairments recognized during the period for long-lived assets held for abandonment, exchange or sale. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 230 -SubTopic 10 -Section 45 -Paragraph 28 -Subparagraph (b) -URI http://asc.fasb.org/extlink&oid=121586364&loc=d3e3602-108585 Reference 2: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 360 -SubTopic 10 -Section 45 -Paragraph 15 -URI http://asc.fasb.org/extlink&oid=109226348&loc=d3e2611-110228 + Details
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- Definition Maximum borrowing capacity under the credit facility without consideration of any current restrictions on the amount that could be borrowed or the amounts currently outstanding under the facility. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 210 -SubTopic 10 -Section S99 -Paragraph 1 -Subparagraph (SX 210.5-02.19(b),22(b)) -URI http://asc.fasb.org/extlink&oid=120391452&loc=d3e13212-122682 + Details
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- Definition The carrying value as of the balance sheet date of the current portion of long-term obligations drawn from a line of credit, which is a bank's commitment to make loans up to a specific amount. Examples of items that might be included in the application of this element may consist of letters of credit, standby letters of credit, and revolving credit arrangements, under which borrowings can be made up to a maximum amount as of any point in time conditional on satisfaction of specified terms before, as of and after the date of drawdowns on the line. Includes short-term obligations that would normally be classified as current liabilities but for which (a) postbalance sheet date issuance of a long term obligation to refinance the short term obligation on a long term basis, or (b) the enterprise has entered into a financing agreement that clearly permits the enterprise to refinance the short-term obligation on a long term basis and the following conditions are met (1) the agreement does not expire within 1 year and is not cancelable by the lender except for violation of an objectively determinable provision, (2) no violation exists at the BS date, and (3) the lender has entered into the financing agreement is expected to be financially capable of honoring the agreement. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 942 -SubTopic 210 -Section S99 -Paragraph 1 -Subparagraph (SX 210.9-03(13)) -URI http://asc.fasb.org/extlink&oid=120398452&loc=d3e534808-122878 Reference 2: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 210 -SubTopic 10 -Section S99 -Paragraph 1 -Subparagraph (SX 210.5-02(19)) -URI http://asc.fasb.org/extlink&oid=120391452&loc=d3e13212-122682 + Details
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