XML 44 R33.htm IDEA: XBRL DOCUMENT v3.21.1
Description of Business and Significant Accounting Policies - Additional Information (Detail)
 1 Months Ended 3 Months Ended
Apr. 22, 2021
USD ($)
Apr. 10, 2020
USD ($)
Mar. 31, 2021
USD ($)
Mar. 31, 2021
USD ($)
Segment
Contract
Mar. 31, 2020
USD ($)
Dec. 31, 2020
USD ($)
Sep. 30, 2020
USD ($)
Dec. 31, 2019
USD ($)
Aug. 31, 2019
USD ($)
Jul. 01, 2013
USD ($)
Organization Consolidation And Presentation Of Financial Statements Disclosure [Line Items]                    
Accumulated deficit     $ (3,062,059,000) $ (3,062,059,000)   $ (3,049,143,000)        
Principal amount     338,400,000 338,400,000            
Cash and cash equivalents     247,833,000 247,833,000   67,005,000        
Short-term investments     28,962,000 28,962,000            
Long-term investments     1,480,000 $ 1,480,000            
Debt issuance amount     $ 230,000,000.0              
Debt issuance percentage     2.50%              
Number of operating segment | Segment       1            
Accretion or amortization       $ 0            
Allowance for credit losses on held-to-maturity securities     $ 0 $ 0            
ASU 2020-06                    
Organization Consolidation And Presentation Of Financial Statements Disclosure [Line Items]                    
Change in accounting principle accounting standards update adopted     true true            
Change in accounting principle accounting standards update adoption date     Jan. 01, 2021 Jan. 01, 2021            
Change in accounting principle accounting standards update immaterial effect     true true            
Change in accounting principle accounting standards update early adoption     true true            
Commitment Asset | Other Expense                    
Organization Consolidation And Presentation Of Financial Statements Disclosure [Line Items]                    
Asset impairment         $ 1,500,000          
Paycheck Protection Program Loan, CARES Act                    
Organization Consolidation And Presentation Of Financial Statements Disclosure [Line Items]                    
Principal amount     $ 4,900,000 $ 4,900,000   4,900,000        
Proceeds from loans   $ 4,900,000                
Insulin                    
Organization Consolidation And Presentation Of Financial Statements Disclosure [Line Items]                    
Loss on purchase commitments     89,100,000 $ 89,100,000   95,300,000        
Loss on purchase commitments, number of new contracts recognized | Contract       0            
Maximum | AFREZZA product sales                    
Organization Consolidation And Presentation Of Financial Statements Disclosure [Line Items]                    
Sales return right following product expiration in months       12 months            
Minimum | AFREZZA product sales                    
Organization Consolidation And Presentation Of Financial Statements Disclosure [Line Items]                    
Sales return right following product expiration in months       6 months            
MidCap Credit Facility                    
Organization Consolidation And Presentation Of Financial Statements Disclosure [Line Items]                    
Principal amount     50,000,000.0 $ 50,000,000.0   $ 50,000,000.0        
Principal amount                 $ 110,000,000.0  
Amount outstanding             $ 50,000,000.0 $ 50,000,000.0    
Commitment asset                 $ 1,500,000  
MidCap Credit Facility | Subsequent Event                    
Organization Consolidation And Presentation Of Financial Statements Disclosure [Line Items]                    
Principal prepayment against outstanding term loans $ 10,000,000.0                  
Milestone Rights Liability | Deerfield                    
Organization Consolidation And Presentation Of Financial Statements Disclosure [Line Items]                    
Contingent liability remain payable     $ 70,000,000.0 $ 70,000,000.0            
Milestone Rights Liability | Maximum | Deerfield                    
Organization Consolidation And Presentation Of Financial Statements Disclosure [Line Items]                    
Contingent liability for milestone payments                   $ 90,000,000.0