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Fair Value of Financial Instruments - Fair Value of Financial Instruments (Detail) - USD ($) $ in Millions | Dec. 31, 2021 | Dec. 31, 2020
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MidCap Credit Facility |  |
Financial liabilities: |  |
Total financial liabilities fair value | $ 40.8 | $ 55.4
Senior convertible notes |  |
Financial liabilities: |  |
Total financial liabilities fair value | 237.5 |
Mann Group Convertible Notes |  |
Financial liabilities: |  |
Total financial liabilities fair value | 37.8 | 52.2
Milestone Rights Liability |  |
Financial liabilities: |  |
Total financial liabilities fair value | 18.1 | 19.8
2024 Convertible Notes |  |
Financial liabilities: |  |
Total financial liabilities fair value |  | 7.0
Mann Group Promissory Notes |  |
Financial liabilities: |  |
Total financial liabilities fair value |  | 78.9
PPP Loan |  |
Financial liabilities: |  |
Total financial liabilities fair value |  | 4.7
Carrying Amount | MidCap Credit Facility |  |
Financial liabilities: |  |
Total financial liabilities fair value | 38.8 | 49.3
Carrying Amount | Senior convertible notes |  |
Financial liabilities: |  |
Total financial liabilities fair value | 223.9 |
Carrying Amount | Mann Group Convertible Notes |  |
Financial liabilities: |  |
Total financial liabilities fair value | 18.4 | 28.0
Carrying Amount | Milestone Rights Liability |  |
Financial liabilities: |  |
Total financial liabilities fair value | 5.9 | 7.3
Carrying Amount | 2024 Convertible Notes |  |
Financial liabilities: |  |
Total financial liabilities fair value |  | 5.0
Carrying Amount | Mann Group Promissory Notes |  |
Financial liabilities: |  |
Total financial liabilities fair value |  | 63.0
Carrying Amount | PPP Loan |  |
Financial liabilities: |  |
Total financial liabilities fair value |  | 4.9
Estimate of Fair Value Measurement | Fair Value, Inputs, Level 3 | MidCap Credit Facility |  |
Financial liabilities: |  |
Total financial liabilities fair value | 40.8 | 55.4
Estimate of Fair Value Measurement | Senior convertible notes | Fair Value, Inputs, Level 3 |  |
Financial liabilities: |  |
Total financial liabilities fair value | 237.5 |
Estimate of Fair Value Measurement | Mann Group Convertible Notes | Fair Value, Inputs, Level 3 |  |
Financial liabilities: |  |
Total financial liabilities fair value | 37.8 |
Estimate of Fair Value Measurement | Milestone Rights Liability | Fair Value, Inputs, Level 3 |  |
Financial liabilities: |  |
Total financial liabilities fair value | $ 18.1 | 19.8
Estimate of Fair Value Measurement | 2024 Convertible Notes | Fair Value, Inputs, Level 3 |  |
Financial liabilities: |  |
Total financial liabilities fair value |  | 7.0
Estimate of Fair Value Measurement | Mann Group Promissory Notes | Fair Value, Inputs, Level 3 |  |
Financial liabilities: |  |
Total financial liabilities fair value |  | 78.9
Estimate of Fair Value Measurement | PPP Loan | Fair Value, Inputs, Level 3 |  |
Financial liabilities: |  |
Total financial liabilities fair value |  | $ 4.7

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- Definition Fair value of financial obligations, including, but not limited to, debt instruments, derivative liabilities, federal funds purchased and sold under agreements to repurchase, securities loaned or sold under agreements to repurchase, financial instruments sold not yet purchased, guarantees, line of credit, loans and notes payable, servicing liability, and trading liabilities. + References No definition available. + Details
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