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Stock Award Plans (Tables) | 12 Months Ended
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Dec. 31, 2021
Disclosure Of Compensation Related Costs Sharebased Payments [Abstract] |
Stock Based Award Plans | The following table summarizes information about the Company’s stock-based award plans as of December 31, 2021:
|  | Outstanding Options |  |  | Outstanding Restricted Stock Units |  |  | Shares Available for Future Issuance |
2004 Equity Incentive Plan |  |  | 206,358 |  |  |  | — |  |  |  | — |
2013 Equity Incentive Plan |  |  | 3,639,936 |  |  |  | 2,600 |  |  |  | — |
2018 Equity Incentive Plan |  |  | 6,800,852 |  |  |  | 7,606,425 |  |  |  | 5,344,810 |
2004 Non-Employee Directors’ Stock Option Plan |  |  | 8,000 |  |  |  | — |  |  |  | — |
Total |  |  | 10,655,146 |  |  |  | 7,609,025 |  |  |  | 5,344,810 |
Stock Based Compensation Expense Recognized in Accompanying Consolidated Statements of Operations by Category | Total stock-based compensation expense recognized in the accompanying consolidated statements of operations is included in the following categories (in thousands):
|  | Year Ended December 31, |
|  | 2021 |  |  | 2020 |
Cost of goods sold |  | $ | 407 |  |  | $ | 446 |
Cost of revenue — collaborations and services |  |  | 1,708 |  |  |  | 626 |
Research and development |  |  | 614 |  |  |  | 338 |
Selling, general and administrative |  |  | 9,471 |  |  |  | 5,101 |
Total |  | $ | 12,200 |  |  | $ | 6,511 |
Assumptions Used to Calculate Fair Value of Employee Stock Options | The Company calculated the fair value of employee stock options granted during the year ended December 31, 2020 using the following assumptions:
|  | Year Ended December 31, |
|  | 2020 |
Risk-free interest rate |  | 0.39% — 1.52% |
Expected lives |  | 5.67 — 7.0 years |
Volatility |  | 93.83% — 94.25% |
Dividends |  |  | — |
Summary of Stock Options Outstanding | The following table summarizes information relating to stock options:
|  | Number of Shares |  |  | Weighted Average Exercise Price per Share |  |  | Weighted Average Remaining Contractual Term (Years) |  |  | Aggregate Intrinsic Value ($000) |
Outstanding at January 1, 2021 |  |  | 12,264,616 |  |  | $ | 3.41 |  |  |  | 6.45 |  |  | $ | 15,414 |
Granted |  |  | — |  |  |  | — |  |  |  |  |  |  |  |  |
Exercised |  |  | (586,572 | ) |  |  | 1.72 |  |  |  |  |  |  |  |  |
Forfeited |  |  | (258,410 | ) |  |  | 1.59 |  |  |  |  |  |  |  |  |
Expired |  |  | (764,488 | ) |  |  | 11.57 |  |  |  |  |  |  |  |  |
Outstanding at December 31, 2021 |  |  | 10,655,146 |  |  | $ | 2.96 |  |  |  | 5.82 |  |  | $ | 25,458 |
Exercisable at December 31, 2021 |  |  | 8,009,961 |  |  | $ | 3.40 |  |  |  | 5.58 |  |  | $ | 18,436 |
Summary of Restricted Stock Unit Activity | The following table summarizes information relating to restricted stock units:
|  | Number of Shares |  |  | Weighted Average Grant Date Fair Value per Share |
Outstanding at January 1, 2021 |  |  | 6,037,542 |  |  | $ | 2.20 |
Granted |  |  | 3,326,798 |  |  |  | 5.82 |
Vested |  |  | (1,516,065 | ) |  |  | 2.22 |
Forfeited |  |  | (239,250 | ) |  |  | 2.58 |
Outstanding at December 31, 2021 |  |  | 7,609,025 |  |  |  | 3.77 |

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- Definition Tabular disclosure of allocation of amount expensed and capitalized for award under share-based payment arrangement to statement of income or comprehensive income and statement of financial position. Includes, but is not limited to, corresponding line item in financial statement. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section 50 -Paragraph 2 -Subparagraph (h)(1) -URI http://asc.fasb.org/extlink&oid=120381028&loc=d3e5070-113901 Reference 2: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section S99 -Paragraph 1 -Subparagraph (SAB Topic 14.F) -URI http://asc.fasb.org/extlink&oid=122041274&loc=d3e301413-122809 Reference 3: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section 50 -Paragraph 1 -Subparagraph (b) -URI http://asc.fasb.org/extlink&oid=120381028&loc=d3e5047-113901 + Details
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- Definition Tabular disclosure for stock option plans. Includes, but is not limited to, outstanding awards at beginning and end of year, grants, exercises, forfeitures, and weighted-average grant date fair value. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section 50 -Paragraph 2 -Subparagraph (d) -URI http://asc.fasb.org/extlink&oid=120381028&loc=d3e5070-113901 Reference 2: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section 50 -Paragraph 2 -Subparagraph (e) -URI http://asc.fasb.org/extlink&oid=120381028&loc=d3e5070-113901 Reference 3: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section 50 -Paragraph 2 -Subparagraph (c)(1) -URI http://asc.fasb.org/extlink&oid=120381028&loc=d3e5070-113901 + Details
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- Definition Tabular disclosure of the significant assumptions used during the year to estimate the fair value of employee stock purchase plans, including, but not limited to: (a) expected term, (b) expected volatility of the entity's shares, (c) expected dividends, (d) risk-free rate(s), and (e) discount for post-vesting restrictions. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section 50 -Paragraph 2 -Subparagraph (f)(2) -URI http://asc.fasb.org/extlink&oid=120381028&loc=d3e5070-113901 + Details
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- Definition Disclosure of the number and weighted-average grant date fair value for restricted stock and restricted stock units that were outstanding at the beginning and end of the year, and the number of restricted stock and restricted stock units that were granted, vested, or forfeited during the year. + References No definition available. + Details
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