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Collaboration, Licensing and Other Arrangements - Additional Information (Detail) - USD ($) |  |  | 1 Months Ended | 12 Months Ended | 20 Months Ended |  |  |  |
--- | --- | --- | --- | --- | --- | --- | --- | --- | ---
Oct. 16, 2021 | Jul. 01, 2021 | May 31, 2018 | Dec. 31, 2021 | Dec. 31, 2020 | Nov. 30, 2020 | Aug. 31, 2021 | Aug. 12, 2021 | Dec. 31, 2019 | Oct. 31, 2018
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |  |  |  |  |
Total transaction price |  |  |  |  | $ 50,900,000 |  |  |  |  |  |
Proceeds from related party |  |  |  |  | 5,000,000.0 |  |  |  |  |  |
Deferred revenue |  |  |  |  | 20,370,000 | $ 34,937,000 |  |  |  | $ 40,847,000 |
Deferred revenue - current |  |  |  |  | 827,000 | 33,275,000 |  |  |  |  |
Deferred revenue - non-current |  |  |  |  | 19,543,000 | 1,662,000 |  |  |  |  |
Revenue' collaborations and services |  |  |  |  | 75,442,000 | 65,144,000 |  |  |  |  |
Deferred revenue |  |  |  |  | 20,370,000 | 34,937,000 |  |  |  | $ 40,847,000 |
Deferred revenue — current |  |  |  |  | 827,000 | 33,275,000 |  |  |  |  |
Deferred revenue — long term |  |  |  |  | 19,543,000 | 1,662,000 |  |  |  |  |
Collaborations and services |  |  |  |  |  |  |  |  |  |  |
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |  |  |  |  |
Revenue' collaborations and services |  |  |  |  | 36,274,000 | 32,820,000 |  |  |  |  |
AFREZZA product sales |  |  |  |  |  |  |  |  |  |  |
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |  |  |  |  |
Revenue' collaborations and services |  |  |  |  | 39,168,000 | 32,324,000 |  |  |  |  |
Collaboration and License Agreement | United Therapeutics Corporation |  |  |  |  |  |  |  |  |  |  |
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |  |  |  |  |
Upfront payment received |  |  |  |  |  |  |  |  |  |  | $ 45,000,000.0
Milestone Payment Received |  |  |  |  |  |  | $ 12,500,000 |  |  |  |
Total transaction price |  |  |  |  | 50,900,000 |  |  |  |  |  |
Total anticipated cash flows | [1] | $ 463,500,000 |  |  |  |  |  |  |  |  |
Deferred revenue |  |  |  |  | 18,600,000 |  |  |  |  |  |
Deferred revenue - current |  |  |  |  | 600,000 |  |  |  |  |  |
Deferred revenue - non-current |  |  |  |  | 18,000,000.0 |  |  |  |  |  |
Deferred revenue |  |  |  |  | 18,600,000 |  |  |  |  |  |
Deferred revenue — current |  |  |  |  | 600,000 |  |  |  |  |  |
Deferred revenue — long term |  |  |  |  | 18,000,000.0 |  |  |  |  |  |
Collaboration and License Agreement | United Therapeutics Corporation | Clinical Supplies |  |  |  |  |  |  |  |  |  |  |
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |  |  |  |  |
Total transaction price |  |  |  |  | 105,800,000 |  |  |  |  |  |
Collaboration and License Agreement | United Therapeutics Corporation | Maximum |  |  |  |  |  |  |  |  |  |  |
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |  |  |  |  |
Additional option exercise and development milestone payments to be receive |  |  |  |  | 40,000,000.0 |  |  |  |  |  |
Collaboration and License Agreement | United Therapeutics Corporation | Manufacturing Services |  |  |  |  |  |  |  |  |  |  |
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |  |  |  |  |
Allocated transaction price |  | 144,500,000 |  |  |  |  |  |  |  |  |
Revenue recognized during period |  |  |  |  | $ 0 |  |  |  |  |  |
Collaboration and License Agreement | United Therapeutics Corporation | Manufacturing Services | Transaction Price For The Contractual Obligations |  |  |  |  |  |  |  |  |  |  |
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |  |  |  |  |
Total anticipated cash flows |  | 64,300,000 |  |  |  |  |  |  |  |  |
Collaboration and License Agreement | United Therapeutics Corporation | Next-Gen R&D Services | Transaction Price For The Performance Obligations |  |  |  |  |  |  |  |  |  |  |
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |  |  |  |  |
Total anticipated cash flows |  | $ 399,200,000 |  |  |  |  |  |  |  |  |
Collaboration and License Agreement | Tyvaso DPI |  |  |  |  |  |  |  |  |  |  |
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |  |  |  |  |
Total anticipated cash flows |  |  |  |  |  |  |  | $ 221,500,000 | $ 221,500,000 |  |
Commercial Supply Agreement |  |  |  |  |  |  |  |  |  |  |
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |  |  |  |  |
Amendment description |  |  |  |  | As amended by an amendment dated October 16, 2021, the term of the CSA continues until December 31, 2031 (unless earlier terminated) and is thereafter renewed automatically for additional, successive two-year terms unless (i) United Therapeutics provides notice to the Company at least 24 months in advance of such renewal that United Therapeutics does not wish to renew the CSA or (ii) the Company provides notice to United Therapeutics at least 48 months in advance of such renewal that the Company does not wish to renew the CSA. |  |  |  |  |  |
Commercial Supply Agreement | United Therapeutics Corporation | Collaborations and services |  |  |  |  |  |  |  |  |  |  |
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |  |  |  |  |
Revenue' collaborations and services |  |  |  |  | $ 267,000 |  |  |  |  |  |
Co-Promotion Agreement |  |  |  |  |  |  |  |  |  |  |
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |  |  |  |  |
Impairment on contract assets related to variable consideration |  |  |  |  | 100,000 |  |  |  |  |  |
Co-Promotion Agreement | Collaborations and services |  |  |  |  |  |  |  |  |  |  |
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |  |  |  |  |
Reserve for allowance for doubtful accounts |  |  |  |  | 800,000 |  |  |  |  |  |
Co-Promotion Agreement | Vertice Pharma LLC |  |  |  |  |  |  |  |  |  |  |
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |  |  |  |  |
Total transaction price |  |  |  |  | 6,300,000 |  |  |  |  |  |
Amendment to Co Promotion Agreement | Vertice Pharma LLC |  |  |  |  |  |  |  |  |  |  |
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |  |  |  |  |
Percentage of modification of previously fixed consideration |  |  | 50.00% |  |  |  |  |  |  |  |
Supply and Distribution Agreement | AFREZZA product sales | Biomm |  |  |  |  |  |  |  |  |  |  |
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |  |  |  |  |
Revenue' collaborations and services |  |  |  |  | 0 | 200,000 |  |  |  |  |
License and Distribution Agreement | Cipla Ltd |  |  |  |  |  |  |  |  |  |  |
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |  |  |  |  |
Deferred revenue |  |  |  |  | 1,700,000 |  |  |  |  |  |
Deferred revenue - current |  |  |  |  | 100,000 |  |  |  |  |  |
Deferred revenue - non-current |  |  |  |  | 1,600,000 |  |  |  |  |  |
Marketing and distribution agreement date |  |  |  | 2018-05 |  |  |  |  |  |  |
Deferred revenue |  |  |  |  | 1,700,000 |  |  |  |  |  |
Deferred revenue — current |  |  |  |  | 100,000 |  |  |  |  |  |
Deferred revenue — long term |  |  |  |  | 1,600,000 |  |  |  |  |  |
License and Distribution Agreement | Collaborations and services | Cipla Ltd |  |  |  |  |  |  |  |  |  |  |
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |  |  |  |  |
Revenue' collaborations and services |  |  |  |  | $ 147,000 | $ 147,000 |  |  |  |  |
[1] | The total anticipated cash flow includes a transaction price of $64.3 million for the contractual obligations under the CSA for the Manufacturing Services and the Next-Gen R&D Services performance obligations and $399.2 million for future supply of Tyvaso DPI over the remaining term of the CSA.

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