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Summary of Significant Accounting Policies - Additional Information (Detail) |  |  | 3 Months Ended | 12 Months Ended |
--- | --- | --- | --- | --- | ---
Jan. 01, 2022 USD ($) | Apr. 10, 2020 USD ($) | Jun. 30, 2020 USD ($) | Dec. 31, 2021 USD ($) Distributor Contract | Dec. 31, 2020 USD ($) | Aug. 31, 2019 USD ($)
Summary Of Significant Accounting Policies [Line Items] |  |  |  |  |  |
Proceeds from loans |  |  |  |  | $ 4,873,000 |
Accretion or amortization |  |  |  | $ 500,000 | $ 0 |
Allowance for credit losses on held-to-maturity securities |  |  |  | $ 0 |  |
Number of wholesale distributors | Distributor |  |  |  | 3 |  |
Percentage of gross sales from major wholesale distributors |  |  |  | 80.00% | 86.00% |
Allowance for accounts receivable |  |  |  | $ 800,000 |  |
Percentage of sales from major customers collaborations and services |  |  |  | 95.00% |  |
Asset impairment |  |  |  | $ 100,000 |  |
ASU 2020-06 |  |  |  |  |  |
Summary Of Significant Accounting Policies [Line Items] |  |  |  |  |  |
Change in accounting principle accounting standards update adopted |  |  |  | true |  |
Change in accounting principle accounting standards update adoption date |  |  |  | Jan. 01, 2021 |  |
Change in accounting principle accounting standards update immaterial effect |  |  |  | true |  |
Commitment Asset | Other Expense |  |  |  |  |  |
Summary Of Significant Accounting Policies [Line Items] |  |  |  |  |  |
Asset impairment |  |  | $ 1,900,000 |  |  |
MidCap Credit Facility |  |  |  |  |  |
Summary Of Significant Accounting Policies [Line Items] |  |  |  |  |  |
Commitment asset |  |  |  |  |  | $ 1,500,000
Other asset |  |  |  |  |  | $ 400,000
Milestone Rights Liability | Deerfield |  |  |  |  |  |
Summary Of Significant Accounting Policies [Line Items] |  |  |  |  |  |
Contingent liability remain payable |  |  |  | $ 65,000,000.0 |  |
Vertice Pharma LLC |  |  |  |  |  |
Summary Of Significant Accounting Policies [Line Items] |  |  |  |  |  |
Allowance for accounts receivable |  |  |  | $ 800,000 |  |
United Therapeutics Corporation |  |  |  |  |  |
Summary Of Significant Accounting Policies [Line Items] |  |  |  |  |  |
Percentage of collaborations and services accounts receivables |  |  |  | 100.00% |  |
Paycheck Protection Program Loan, CARES Act |  |  |  |  |  |
Summary Of Significant Accounting Policies [Line Items] |  |  |  |  |  |
Proceeds from loans |  | $ 4,900,000 |  |  |  |
Convertible Promissory Note | Thirona Bio, Inc. |  |  |  |  |  |
Summary Of Significant Accounting Policies [Line Items] |  |  |  |  |  |
Investment securities |  |  |  | $ 3,000,000.0 |  |
Proceeds from investment securities |  |  |  | $ 3,000,000.0 |  |
Maturity date |  |  |  | Dec. 31, 2023 |  |
Interest rate |  |  |  | 6.00% |  |
Convertible Promissory Note | Subsequent Event | Thirona Bio, Inc. |  |  |  |  |  |
Summary Of Significant Accounting Policies [Line Items] |  |  |  |  |  |
Investment securities | $ 5,000,000.0 |  |  |  |  |
Proceeds from investment securities | $ 5,000,000.0 |  |  |  |  |
AFREZZA product sales |  |  |  |  |  |
Summary Of Significant Accounting Policies [Line Items] |  |  |  |  |  |
Percentage of accounts receivable from major wholesale distributors |  |  |  | 79.00% | 90.00% |
Insulin |  |  |  |  |  |
Summary Of Significant Accounting Policies [Line Items] |  |  |  |  |  |
Loss on purchase commitments |  |  |  | $ 82,800,000 | $ 95,300,000 |
Loss on purchase commitments, number of new contracts recognized | Contract |  |  |  | 0 |  |
Minimum | AFREZZA product sales |  |  |  |  |  |
Summary Of Significant Accounting Policies [Line Items] |  |  |  |  |  |
Sales return right following product expiration in months |  |  |  | 6 months |  |
Maximum | AFREZZA product sales |  |  |  |  |  |
Summary Of Significant Accounting Policies [Line Items] |  |  |  |  |  |
Sales return right following product expiration in months |  |  |  | 12 months |  |

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