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Schedule of Revenue from Collaborations and Services (Detail) - USD ($) $ in Thousands | 1 Months Ended | 3 Months Ended | 6 Months Ended
--- | --- | --- | ---
Jun. 30, 2022 | Jun. 30, 2022 | Jun. 30, 2021 | Jun. 30, 2022 | Jun. 30, 2021
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] |  |  |  |  |  |
Total revenue from collaborations and services |  |  | $ 18,894 | $ 23,280 | $ 30,886 | $ 40,716
United Therapeutics Corporation |  |  |  |  |  |
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] |  |  |  |  |  |
Total revenue from collaborations and services |  |  | 5,697 | 12,163 | 7,739 | 21,163
License Agreement | United Therapeutics Corporation |  |  |  |  |  |
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] |  |  |  |  |  |
Total revenue from collaborations and services |  |  | 698 | 12,163 | 1,556 | 21,163
Commercial Supply Agreement | United Therapeutics Corporation |  |  |  |  |  |
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] |  |  |  |  |  |
Total revenue from collaborations and services |  |  | 4,695 |  | 5,879 |
Collaborations and services |  |  |  |  |  |
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] |  |  |  |  |  |
Total revenue from collaborations and services |  |  | 5,868 | 13,304 | 8,034 | 22,641
Collaborations and services | License Agreement | United Therapeutics Corporation |  |  |  |  |  |
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] |  |  |  |  |  |
Total revenue from collaborations and services | [1] |  | 698 | 12,163 | 1,556 | 21,163
Collaborations and services | Commercial Supply Agreement | United Therapeutics Corporation |  |  |  |  |  |
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] |  |  |  |  |  |
Total revenue from collaborations and services | [2] |  | 4,695 |  | 5,879 |
Collaborations and services | License and Distribution Agreement | Cipla Ltd |  |  |  |  |  |
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] |  |  |  |  |  |
Total revenue from collaborations and services |  |  | 36 | 37 | 73 | 73
Collaborations and services | Other |  |  |  |  |  |
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] |  |  |  |  |  |
Total revenue from collaborations and services |  |  | 114 | 83 | 201 | 83
Collaborations and services | Co-Promotion Agreement | Vertice Pharma LLC |  |  |  |  |  |
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] |  |  |  |  |  |
Total revenue from collaborations and services |  | $ 300 | $ 325 | 856 | $ 325 | 1,147
Collaborations and services | Collaboration and License Agreement | Receptor CLA |  |  |  |  |  |
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] |  |  |  |  |  |
Total revenue from collaborations and services |  |  |  | $ 165 |  | $ 175
[1] | Amounts consist of revenue recognized for Next-Gen R&D Services and R&D Services and License for the periods presented.
[2] | Amount consists of revenue recognized for Manufacturing Services and sales of product to UT for the periods presented.

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