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Collaboration, Licensing and Other Arrangements - Additional Information (Detail) - USD ($) |  | 1 Months Ended | 3 Months Ended | 9 Months Ended | 12 Months Ended | 20 Months Ended |
--- | --- | --- | --- | --- | --- | --- | ---
Oct. 31, 2021 | Jun. 30, 2022 | Apr. 30, 2022 | May 31, 2018 | Sep. 30, 2022 | Sep. 30, 2021 | Sep. 30, 2022 | Sep. 30, 2021 | Dec. 31, 2021 | Nov. 30, 2020 | Oct. 31, 2018
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |
Deferred revenue - current |  |  |  |  |  |  |  | $ 1,786,000 |  | $ 1,786,000 |  | $ 827,000 |  |
Deferred revenue - non-current |  |  |  |  |  |  |  | 31,996,000 |  | 31,996,000 |  | 19,543,000 |  |
Total revenue from collaborations and services |  |  |  |  |  |  |  | 32,825,000 | $ 22,211,000 | 63,711,000 | $ 62,927,000 |  |  |
Collaborations and services |  |  |  |  |  |  |  |  |  |  |  |  |  |
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |
Total revenue from collaborations and services |  |  |  |  |  |  |  | 10,346,000 | 12,458,000 | 18,380,000 | 35,099,000 |  |  |
Commercial product sales |  |  |  |  |  |  |  |  |  |  |  |  |  |
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |
Total revenue from collaborations and services |  |  |  |  |  |  |  | 16,259,000 | 9,753,000 | 38,807,000 | 27,828,000 |  |  |
United Therapeutics Corporation |  |  |  |  |  |  |  |  |  |  |  |  |  |
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |
Total revenue from collaborations and services |  |  |  |  |  |  |  | 16,529,000 | 12,313,000 | 24,268,000 | 33,475,000 |  |  |
United Therapeutics Corporation | Manufacturing Services |  |  |  |  |  |  |  |  |  |  |  |  |  |
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |
Funding for development of alternative manufacturing processes |  |  |  |  | $ 700,000 |  |  |  |  |  |  |  |  |
United Therapeutics Corporation | Commercialization and Continuous Improvement Activities |  |  |  |  |  |  |  |  |  |  |  |  |  |
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |
Funding for capital improvements |  |  |  |  | 2,300,000 |  |  |  |  |  |  |  |  |
Collaboration and License Agreement | United Therapeutics Corporation |  |  |  |  |  |  |  |  |  |  |  |  |  |
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |
Upfront payment received |  |  |  |  |  |  |  |  |  |  |  |  |  | $ 45,000,000.0
Milestone Payment Received |  |  |  |  |  |  |  |  |  |  |  |  | $ 12,500,000 |
Total anticipated cash flow |  | $ 463,500,000 | [1] |  | 483,200,000 | [2] |  |  |  |  |  |  |  |
Deferred revenue |  |  |  |  |  |  |  | 32,200,000 |  | 32,200,000 |  |  |  |
Deferred revenue - current |  |  |  |  |  |  |  | 1,600,000 |  | 1,600,000 |  |  |  |
Deferred revenue - non-current |  |  |  |  |  |  |  | 30,600,000 |  | 30,600,000 |  |  |  |
Collaboration and License Agreement | United Therapeutics Corporation | Manufacturing Services |  |  |  |  |  |  |  |  |  |  |  |  |  |
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |
Allocated transaction price including material right |  | 144,500,000 |  |  | 150,200,000 |  |  |  |  |  |  |  |  |
Collaboration and License Agreement | United Therapeutics Corporation | Manufacturing Services | Transaction Price For The Contractual Obligations |  |  |  |  |  |  |  |  |  |  |  |  |  |
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |
Total anticipated cash flow |  | 64,300,000 |  |  | 71,500,000 |  |  |  |  |  |  |  |  |
Collaboration and License Agreement | United Therapeutics Corporation | Next-Gen R&D Services | Transaction Price For The Performance Obligations |  |  |  |  |  |  |  |  |  |  |  |  |  |
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |
Total anticipated cash flow |  | $ 399,200,000 |  |  | $ 411,700,000 |  |  |  |  |  |  |  |  |
Collaboration and License Agreement | United Therapeutics Corporation | Maximum |  |  |  |  |  |  |  |  |  |  |  |  |  |
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |
Additional option exercise and development milestone payments to be receive |  |  |  |  |  |  |  | 40,000,000.0 |  | $ 40,000,000.0 |  |  |  |
Commercial Supply Agreement |  |  |  |  |  |  |  |  |  |  |  |  |  |
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |
Amendment description |  |  |  |  |  |  |  |  |  | The term of the CSA continues until December 31, 2031 (unless earlier terminated) and is thereafter renewed automatically for additional, successive two-year terms unless (i) UT provides notice to the Company at least 24 months in advance of such renewal that UT does not wish to renew the CSA or (ii) the Company provides notice to UT at least 48 months in advance of such renewal that the Company does not wish to renew the CSA. |  |  |  |
Commercial Supply Agreement | United Therapeutics Corporation |  |  |  |  |  |  |  |  |  |  |  |  |  |
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |
Total revenue from collaborations and services |  |  |  |  |  |  |  | 9,916,000 |  | $ 15,795,000 |  |  |  |
Commercial Supply Agreement | United Therapeutics Corporation | Collaborations and services |  |  |  |  |  |  |  |  |  |  |  |  |  |
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |
Total revenue from collaborations and services | [3] |  |  |  |  |  |  | 9,916,000 |  | 15,795,000 |  |  |  |
Co-Promotion Agreement | Collaborations and services |  |  |  |  |  |  |  |  |  |  |  |  |  |
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |
Reserve for allowance for credit losses |  |  |  |  |  |  |  |  |  |  |  | 800,000 |  |
Co-Promotion Agreement | Collaborations and services | Vertice Pharma LLC |  |  |  |  |  |  |  |  |  |  |  |  |  |
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |
Total revenue from collaborations and services |  |  |  | $ 300,000 |  |  |  |  |  | 325,000 | 1,147,000 |  |  |
Supply and Distribution Agreement | Commercial product sales | Biomm |  |  |  |  |  |  |  |  |  |  |  |  |  |
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |
Total revenue from collaborations and services |  |  |  |  |  |  |  |  |  | 0 |  | $ 0 |  |
License and Distribution Agreement | Cipla Ltd |  |  |  |  |  |  |  |  |  |  |  |  |  |
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |
Deferred revenue |  |  |  |  |  |  |  | 1,600,000 |  | 1,600,000 |  |  |  |
Deferred revenue - current |  |  |  |  |  |  |  | 200,000 |  | 200,000 |  |  |  |
Deferred revenue - non-current |  |  |  |  |  |  |  | 1,400,000 |  | 1,400,000 |  |  |  |
Marketing and distribution agreement date |  |  |  |  |  |  | 2018-05 |  |  |  |  |  |  |
License and Distribution Agreement | Collaborations and services | Cipla Ltd |  |  |  |  |  |  |  |  |  |  |  |  |  |
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items] |  |  |  |  |  |  |  |  |  |  |  |  |  |
Total revenue from collaborations and services |  |  |  |  |  |  |  | $ 37,000 | $ 37,000 | $ 110,000 | $ 110,000 |  |  |
[1] | The total anticipated cash flow includes a transaction price of $64.3 million for the contractual obligations under the CSA for the Manufacturing Services and the Next-Gen R&D Services performance obligations and $399.2 million for future supply of Tyvaso DPI over the remaining term of the CSA.
[2] | The total anticipated cash flow includes a transaction price of $71.5 million for the contractual obligations under the CSA for the Manufacturing Services and the Next-Gen R&D Services performance obligations and $411.7 million for future supply of Tyvaso DPI over the remaining term of the CSA.
[3] | Amount consists of revenue recognized for Manufacturing Services and sales of product to UT for the periods presented.

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