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Accounts Receivable - Additional Information (Detail) | 12 Months Ended
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Dec. 31, 2022 USD ($) Distributor | Dec. 31, 2021 Distributor
Accounts Receivable [Line Items] |  |
Number of wholesale distributors | Distributor | 3 | 3
Percentage of gross sales from major wholesale distributors | 79.00% | 79.00%
Allowance for credit losses for accounts receivable | $ | $ 0 |
Percentage of revenue from major customers collaborations and services | 98.00% |
United Therapeutics Corporation |  |
Accounts Receivable [Line Items] |  |
Percentage of collaborations and services net accounts receivables | 100.00% |
Commercial product sales |  |
Accounts Receivable [Line Items] |  |
Percentage of accounts receivable from major wholesale distributors | 74.00% | 80.00%

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