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Accounts Receivable - Additional Information (Detail)	12 Months Ended
	Dec. 31, 2022 USD ($) Distributor	Dec. 31, 2021 Distributor
Accounts Receivable [Line Items]
Number of wholesale distributors | Distributor	3	3
Percentage of gross sales from major wholesale distributors	79.00%	79.00%
Allowance for credit losses for accounts receivable | $	$ 0
Percentage of revenue from major customers collaborations and services	98.00%
United Therapeutics Corporation
Accounts Receivable [Line Items]
Percentage of collaborations and services net accounts receivables	100.00%
Commercial product sales
Accounts Receivable [Line Items]
Percentage of accounts receivable from major wholesale distributors	74.00%	80.00%

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Reference 1: http://www.xbrl.org/2003/role/disclosureRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 310
-SubTopic 10
-Section 50
-Paragraph 4
-URI https://asc.fasb.org/extlink&oid=123577603&loc=d3e5074-111524

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