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Consolidated Statements of Cash Flows - USD ($)
$ in Thousands
 12 Months Ended
Dec. 31, 2022
Dec. 31, 2021
Dec. 31, 2020
CASH FLOWS FROM OPERATING ACTIVITIES:      
Net loss $ (87,400) $ (80,926) $ (57,240)
Adjustments to reconcile net loss to net cash used in operating activities:      
Stock-based compensation expense 13,447 12,200 6,511
Depreciation, amortization and accretion 6,124 4,215 2,149
Interest expense on financing liability 9,552 1,372  
Interest on milestone right   3,663  
Write-off of inventory 2,202 1,902 496
Interest expense on Mann Group promissory notes 325 1,598 5,148
Amortization of right-of-use assets 2,987 1,258 1,177
Loss on available-for-sale securities 932    
Loss on extinguishment of debt, net   17,200 264
Asset impairment   106 1,889
(Gain) loss on foreign currency translation (4,811) (6,567) 8,006
In-process research and development     13,233
Other, net 17   19
Changes in operating assets and liabilities:      
Accounts receivable, net (11,807) (776) (705)
Inventory (5,670) (4,081) (1,314)
Prepaid expenses and other current assets (15,552) (360) (154)
Other assets 523 (138) 227
Accounts payable 4,096 1,374 793
Accrued expenses and other current liabilities (723) 8,814 3,346
Deferred revenue 19,047 (14,567) (5,910)
Recognized loss on purchase commitments (5,709) (5,892) (4,751)
Operating lease liabilities (3,309) (2,135) (1,312)
Accrued interest on Mann Group promissory notes   (4,919)  
Deposits from customer (4,950) 4,950  
Net cash used in operating activities (80,679) (61,709) (28,128)
CASH FLOWS FROM INVESTING ACTIVITIES:      
Purchase of held-to-maturity debt securities (74,536) (196,131)  
Proceeds from maturity of debt securities 107,340 59,060  
Acquisition of V-Go (15,341)    
Purchase of property and equipment (7,589) (11,466) (801)
Purchase of available-for-sale securities (5,000) (3,000)  
Proceeds from sale of treasury bills     20,000
Acquisition of in-process research and development, net of cash acquired     (3,983)
Net cash provided by (used in) investing activities 4,874 (151,537) 15,216
CASH FLOWS FROM FINANCING ACTIVITIES:      
Milestone payment (1,088) (5,000)  
Issuance costs associated with the sale-leaseback transaction   (3,120)  
Net issuance of common stock associated with stock options and restricted stock units 319 (498) 233
Proceeds from market price stock purchase plan and from employee stock purchase plan 2,766 106 215
Payment on financing liability (18)    
Issuance of common stock from the exercise of warrants     11,600
Proceeds from MidCap credit facility     10,000
Proceeds from PPP loan     4,873
Proceeds from the Senior convertible notes   230,000  
Issuance costs associated with Senior convertible notes   (7,268)  
Proceeds from the sale-leaseback transaction   102,250  
Deposit for the sale-leaseback transaction   (2,000)  
Principal payments on Mann Group promissory notes   (35,051)  
Payment of MidCap credit facility   (10,000)  
Payment of MidCap credit facility prepayment penalty   (1,000)  
Net cash provided by financing activities 21,388 270,267 49,853
NET INCREASE IN CASH AND CASH EQUIVALENTS AND RESTRICTED CASH (54,417) 57,021 36,941
CASH AND CASH EQUIVALENTS AND RESTRICTED CASH, BEGINNING OF PERIOD 124,184 67,163 30,222
CASH AND CASH EQUIVALENTS AND RESTRICTED CASH, END OF PERIOD 69,767 124,184 67,163
SUPPLEMENTAL CASH FLOWS DISCLOSURES:      
Interest paid in cash 8,852 11,268 3,558
NON-CASH INVESTING AND FINANCING ACTIVITIES:      
Reclassification of investments from long-term to current 82,850 32,654  
Reclassification of Thirona convertible notes and interest receivable from long-term to current 7,375    
Payments on debt and interest through common stock issuance 10,270 15,143 15,549
Forgiveness of PPP loan   (4,873)  
Addition of right-of-use-asset 1,812 1,425  
Right-of-use asset modification 3,793 278  
Non-cash construction in progress and property and equipment 1,298 1,264 92
Issuance of common stock under Employee Stock Purchase Plan   1,090 684
Contingent milestone liability 610    
Issuance of common stock for acquisition of in-process research and development     9,250
Issuance of warrants associated with the MidCap Credit Facility     275
Receivable from at-the-market offering     226
The Mann Group L L C      
NON-CASH INVESTING AND FINANCING ACTIVITIES:      
Premium on convertible note   22,107  
At The Market Issuance      
CASH FLOWS FROM FINANCING ACTIVITIES:      
Proceeds from public offering 19,790 1,886 23,450
Issuance costs associated with the sale-leaseback transaction $ (381) $ (38) $ (518)