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Fair Value of Financial Instruments - Fair Value of Financial Instruments (Detail) - USD ($) $ in Millions	Dec. 31, 2022	Dec. 31, 2021	Nov. 30, 2021
MidCap Credit Facility
Financial liabilities:
Total financial liabilities fair value	$ 41.1	$ 40.8
Total financial liabilities fair value	41.1	40.8
Fair Value, Inputs, Level 3
Financial liabilities:
Total financial liabilities fair value			$ 103.2
Total financial liabilities fair value			$ 103.2
Mann Group Convertible Note
Financial liabilities:
Total financial liabilities fair value	20.8	37.8
Total financial liabilities fair value	20.8	37.8
Contingent Milestone Liability
Financial liabilities:
Total financial liabilities fair value	1.0
Total financial liabilities fair value	1.0
Milestone Rights Liability
Financial liabilities:
Total financial liabilities fair value	12.6	18.1
Total financial liabilities fair value	12.6	18.1
Senior Convertible Notes
Financial liabilities:
Total financial liabilities fair value	253.9	237.5
Total financial liabilities fair value	253.9	237.5
Carrying Amount | MidCap Credit Facility
Financial liabilities:
Total financial liabilities fair value	39.3	38.8
Total financial liabilities fair value	39.3	38.8
Carrying Amount | Mann Group Convertible Note
Financial liabilities:
Total financial liabilities fair value	8.8	18.4
Total financial liabilities fair value	8.8	18.4
Carrying Amount | Contingent Milestone Liability
Financial liabilities:
Total financial liabilities fair value	0.6
Total financial liabilities fair value	0.6
Carrying Amount | Milestone Rights Liability
Financial liabilities:
Total financial liabilities fair value	4.8	5.9
Total financial liabilities fair value	4.8	5.9
Carrying Amount | Senior Convertible Notes
Financial liabilities:
Total financial liabilities fair value	225.4	223.9
Total financial liabilities fair value	225.4	223.9
Estimate of Fair Value Measurement | Fair Value, Inputs, Level 3 | MidCap Credit Facility
Financial liabilities:
Total financial liabilities fair value	41.1	40.8
Total financial liabilities fair value	41.1	40.8
Estimate of Fair Value Measurement | Mann Group Convertible Note | Fair Value, Inputs, Level 3
Financial liabilities:
Total financial liabilities fair value	20.8	37.8
Total financial liabilities fair value	20.8	37.8
Estimate of Fair Value Measurement | Contingent Milestone Liability | Fair Value, Inputs, Level 3
Financial liabilities:
Total financial liabilities fair value	1.0
Total financial liabilities fair value	1.0
Estimate of Fair Value Measurement | Milestone Rights Liability | Fair Value, Inputs, Level 3
Financial liabilities:
Total financial liabilities fair value	12.6	18.1
Total financial liabilities fair value	12.6	18.1
Estimate of Fair Value Measurement | Senior Convertible Notes | Fair Value, Inputs, Level 3
Financial liabilities:
Total financial liabilities fair value	253.9	237.5
Total financial liabilities fair value	$ 253.9	$ 237.5

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- Definition

Fair value of financial obligations, including, but not limited to, debt instruments, derivative liabilities, federal funds purchased and sold under agreements to repurchase, securities loaned or sold under agreements to repurchase, financial instruments sold not yet purchased, guarantees, line of credit, loans and notes payable, servicing liability, and trading liabilities.

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